Emergent synapse organizers: LAR-RPTPs and their companions. (Record no. 52097)

MARC details
000 -LEADER
fixed length control field 01998nam a2200313Ia 4500
003 - CONTROL NUMBER IDENTIFIER
control field MX-MdCICY
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250625160220.0
040 ## - CATALOGING SOURCE
Transcribing agency CICY
090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN)
Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-17937
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245 10 - TITLE STATEMENT
Title Emergent synapse organizers: LAR-RPTPs and their companions.
490 0# - SERIES STATEMENT
Volume/sequential designation In International Review of cell and Molecular Biology. Academic Press., 324, p.39-65, 2016
520 3# - SUMMARY, ETC.
Summary, etc. Leukocyte common antigen-related receptor tyrosine phosphatases (LAR-RPTPs)have emerged as key players that organize various aspects of neuronal development, including axon guidance, neurite extension, and synapse formation and function. Recent research has highlighted the roles of LAR-RPTPs at neuronal synapses in mediating distinct synaptic adhesion pathways through interactions with a host of extracellular ligands and in governing a variety of intracellular signaling cascades through binding to various scaffolds and signaling proteins. In this chapter, we review and update current research progress on the extracellular ligands of LAR-RPTPs, regulation of their extracellular interactions by alternative splicing and heparan sulfates, and their intracellular signaling machineries. In particular, we review structural insights on complexes of LAR-RPTPs with their various ligands. These studies lend support to general molecular mechanisms underlying LAR-RPTP-mediated synaptic adhesion and signaling pathways.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element LAR
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element PTP
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element PTP
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element SYNAPTIC ADHESIÓN
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element RECEPTOR PROTEIN TYROSINE PHOSPHATASE
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element LIGANDS
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element SYNAPSE DEVELOPMENT
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element ALTERNATIVE SPLICING
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element HEPARAN SULFATE
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Han, K. A.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Jeon, S.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Um, J. W.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Ko, J.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1Q983Q7D947AES_tK2wBMdgg6RElFgb2i/view?usp=drivesdk">https://drive.google.com/file/d/1Q983Q7D947AES_tK2wBMdgg6RElFgb2i/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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Source of classification or shelving scheme Clasificación local
Koha item type Documentos solicitados
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-17937 25.06.2025 25.06.2025 Documentos solicitados