MARC details
| 000 -LEADER |
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| fixed length control field |
01996nam a2200313Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20250625160222.0 |
| 040 ## - CATALOGING SOURCE |
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| Transcribing agency |
CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) |
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| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) |
B-18035 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT |
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| Title |
Leishmanicidal activity of green tea leaves and pomegranate peel extracts on L. infantum. |
| 490 0# - SERIES STATEMENT |
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| Volume/sequential designation |
Natural Product Research, 33(24), p.3465-3471, 2019 |
| 520 3# - SUMMARY, ETC. |
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| Summary, etc. |
Leishmania infantum is responsible for the cutaneous and visceral form of this zoonotic disease, which is potentially lethal for humans and has dogs as natural reservoir. In the light of the antiparasitic properties displayed by several natural products, L. infantum promastigotes were exposed to green tea (Camellia sinensis)leaves extract (GTE)and pomegranate (Punica granatum)peel extract (PPE). Both extracts, characterized by NMR and HPLC analysis, inhibited parasite proliferation in a dose-dependent manner, as proved by IC50 evaluation determined by MTT assay.Moreover, the reversibility assay showed that GTE and PPE have an aptotosis-mediated leishmanicidal effect, as evidenced by DNA degradation and confirmed by DNA fragmentation and real-time PCR analyses. Finally, for the first time morphological and ultrastructural alterations induced by a P. granatum extract on Leishmania were shown by the use of light, transmission and scanning electron microscopy. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
CAMELLIA SINENSIS |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
PUNICA GRANATUM |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
LEISHMANIA INFANTUM PROMASTIGOTES |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
POMEGRANATE PEEL EXTRACT |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
GREEN TEA LEAVES EXTRACT |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
LEISHMANICIDAL AGENTS |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Imperatori, F. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Barlozzari, G. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Scardigli, A. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Romani, A. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Macrì, G. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Polinori, N. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Santi, L. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
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| Uniform Resource Identifier |
<a href="https://drive.google.com/file/d/1NdWjIxWpJQROKomT5_8p3lkTz7hS65vt/view?usp=drivesdk">https://drive.google.com/file/d/1NdWjIxWpJQROKomT5_8p3lkTz7hS65vt/view?usp=drivesdk</a> |
| Public note |
Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Source of classification or shelving scheme |
Clasificación local |
| Koha item type |
Documentos solicitados |
