Synthesis and biological evaluation of C-13, C-14 modified taxane analogues from 1-deoxybaccatin VI. (Record no. 52195)

MARC details
000 -LEADER
fixed length control field 01212nam a2200265Ia 4500
003 - CONTROL NUMBER IDENTIFIER
control field MX-MdCICY
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250625160222.0
040 ## - CATALOGING SOURCE
Transcribing agency CICY
090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN)
Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-18036
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245 10 - TITLE STATEMENT
Title Synthesis and biological evaluation of C-13, C-14 modified taxane analogues from 1-deoxybaccatin VI.
490 0# - SERIES STATEMENT
Volume/sequential designation Natural Product Research, 33(24), p.3478-3484, 2019
520 3# - SUMMARY, ETC.
Summary, etc. our C-13, C-14 side chain modified 9(R)-hydroxy-1-deoxy-taxane analogues 15, 16, 19 and 22 were semi-synthesized from 1-deoxybaccatin VI. The in vitro antitumor activity of these compounds was evaluated against A549 and A2780 cell lines. The preliminary SAR analysis showed that introduction of oxygen-containing group on C-14 could improve the cytotoxic activities.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element 1-DEOXYBACCATIN VI
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element TAXANE
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element CYTOTOXICITY
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Topical term or geographic name entry element OXIDATION
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element SYNTHESIS
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Tang, P.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Lin, H. X.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Yuan, T. H.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Cui, Y. M.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/13_-dOfCiQFwRqElhG1uxktUxkLUAN_6H/view?usp=drivesdk">https://drive.google.com/file/d/13_-dOfCiQFwRqElhG1uxktUxkLUAN_6H/view?usp=drivesdk</a>
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942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Clasificación local
Koha item type Documentos solicitados
Holdings
Lost status Source of classification or shelving scheme Damaged status Not for loan Collection Home library Current library Shelving location Date acquired Total checkouts Full call number Date last seen Price effective from Koha item type
  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-18036 25.06.2025 25.06.2025 Documentos solicitados