Evolutionary classification of CRISPR-Cas systems: a burst of class 2 and derived variants. (Record no. 52244)

MARC details
000 -LEADER
fixed length control field 02048nam a2200277Ia 4500
003 - CONTROL NUMBER IDENTIFIER
control field MX-MdCICY
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250625160223.0
040 ## - CATALOGING SOURCE
Transcribing agency CICY
090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN)
Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-18086
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 250602s9999 xx |||||s2 |||| ||und|d
245 10 - TITLE STATEMENT
Title Evolutionary classification of CRISPR-Cas systems: a burst of class 2 and derived variants.
490 0# - SERIES STATEMENT
Volume/sequential designation Nature Reviews MicroBiology, p.1-17, 2019
520 3# - SUMMARY, ETC.
Summary, etc. The number and diversity of known CRISPR-Cas systems have substantially increased in recent years. Here, we provide an updated evolutionary classification of CRISPR-Cas systems and cas genes, with an emphasis on the major developments that have occurred since the publication of the latest classification, in 2015. The new classification includes 2 classes, 6 types and 33 subtypes, compared with 5 types and 16 subtypes in 2015. A key development is the ongoing discovery of multiple, novel class 2 CRISPR-Cas systems, which now include 3 types and 17 subtypes. A second major novelty is the discovery of numerous derived CRISPR-Cas variants, often associated with mobile genetic elements that lack the nucleases required for interference. Some of these variants are involved in RNA-guided transposition, whereas others are predicted to perform functions distinct from adaptive immunity that remain to be characterized experimentally. The third highlight is the discovery of numerous families of ancillary CRISPR-linked genes, often implicated in signal transduction. Together, these findings substantially clarify the functional diversity and evolutionary history of CRISPR-Cas.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element CRISPR
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element ADAPTATION
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element CRISPR-CAS
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Makarova, K. S.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Wolf, Y. I.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Iranzo, J.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Shmakov, S. A.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Alkhnbashi, O. S.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Brouns, S. J.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Moineau, S.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1v2x7htxyzIrvNqaROLOJK-pxm99M9gtQ/view?usp=drivesdk">https://drive.google.com/file/d/1v2x7htxyzIrvNqaROLOJK-pxm99M9gtQ/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Clasificación local
Koha item type Documentos solicitados
Holdings
Lost status Source of classification or shelving scheme Damaged status Not for loan Collection Home library Current library Shelving location Date acquired Total checkouts Full call number Date last seen Price effective from Koha item type
  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-18086 25.06.2025 25.06.2025 Documentos solicitados