Evolution and molecular mechanism of CRISPR/Cas9 systems. (Record no. 52334)

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control field MX-MdCICY
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control field 20250625160224.0
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Transcribing agency CICY
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Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-18181
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Title Evolution and molecular mechanism of CRISPR/Cas9 systems.
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Volume/sequential designation In Genome Engineering via CRISPR-Cas9 System. Academic Press., p.15-25, 2020
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Summary, etc. CRISPR/Cas module is an RNA-guided adaptive immune system, provides sequence-specific immunity against phages and (conjugative)plasmids. CRISPR/Cas system is basically categorized into three types: (type I, II and III), on the basis of effector complexes. CRISPR/Cas9 system is repercussion of evolutionary everlasting arm race between bacteria and phages. Molecular mechanism underlying the CRISPR system entails three distinct mechanistic stages: spacer acquisition, crRNA biogenesis and interference. CRISPR/Cas9 system composed of a combination of Cas9 (an endonuclease)and a customizable single guide RNA (sgRNA), the later directs the Cas9 for recognition and degradation of invading DNA. Furthermore, Cas9 and their ilk proteins with unique properties have opened a plethora of options including DNA/RNA genome targeting, transcription/translation regulation and empower researchers to edit genes with highly precision and speed.
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Topical term or geographic name entry element BACTERIA
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Topical term or geographic name entry element CASCADE
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Topical term or geographic name entry element CRISPR/CAS SYSTEMS
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Topical term or geographic name entry element DCAS9
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Topical term or geographic name entry element GENOME EDITING
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Topical term or geographic name entry element RNA
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Personal name Bhushan, K.
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Uniform Resource Identifier <a href="https://drive.google.com/file/d/1OYdwUhuslep28rATaBWT__U21w7iUh83/view?usp=drivesdk">https://drive.google.com/file/d/1OYdwUhuslep28rATaBWT__U21w7iUh83/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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Source of classification or shelving scheme Clasificación local
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-18181 25.06.2025 25.06.2025 Documentos solicitados