Mesenchymal stem cells combined with an artificial dermal substitute improve repair in full-thickness skin wounds. (Record no. 52401)

MARC details
000 -LEADER
fixed length control field 02313nam a2200289Ia 4500
003 - CONTROL NUMBER IDENTIFIER
control field MX-MdCICY
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250625160226.0
040 ## - CATALOGING SOURCE
Transcribing agency CICY
090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN)
Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-18248
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 250602s9999 xx |||||s2 |||| ||und|d
245 10 - TITLE STATEMENT
Title Mesenchymal stem cells combined with an artificial dermal substitute improve repair in full-thickness skin wounds.
490 0# - SERIES STATEMENT
Volume/sequential designation Burns, 38(8), p.1143-1150, 2012
520 3# - SUMMARY, ETC.
Summary, etc. Autografts represent the gold standard for the treatment of full thickness burns. Factors such as lack of suitable donor sites and poor skin quality, however, have led to the development of artificial dermal substitutes. The investigation of mechanisms leading to enhanced functionality of these skin substitutes has been attracting great attention. This study aimed to investigate the effect of autologous stem cells on the integration and vascularization of a dermal substitute in full-thickness skin wounds, in a murine model. Two cell populations were compared, whole bone marrow cells and cultivated mesenchymal stem cells, isolated from mice transgenic for the enhanced green fluorescent protein, which allowed tracking of the transplanted cells. The number of cells colonizing the dermal substitute, as well as vascular density, were higher in mice receiving total bone marrow and particularly mesenchymal stem cells, than in control animals. The effect was more pronounced in animals treated with mesenchymal stem cells, which located primarily in the wound bed, suggesting a paracrine therapeutic mechanism. These results indicate that combining mesenchymal stem cells with artificial dermal substitutes may represent an important potential modality for treating full thickness burns, even in allogeneic combinations due to the immunoregulatory property of these cells.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element BURN CARE
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element MESENCHYMAL STEM CELL
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element WOUND HEALING
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element SKIN SUBSTITUTE
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Leonardi, D.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Oberdoerfer, D.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Fernandes, M. C.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Meurer, R. T.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Pereira-Filho, G. A.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Cruz, P.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Nardi, N. B.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1xVIduomc2sIT2rRg9DaYX7GxkmrV-VMq/view?usp=drivesdk">https://drive.google.com/file/d/1xVIduomc2sIT2rRg9DaYX7GxkmrV-VMq/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Clasificación local
Koha item type Documentos solicitados
Holdings
Lost status Source of classification or shelving scheme Damaged status Not for loan Collection Home library Current library Shelving location Date acquired Total checkouts Full call number Date last seen Price effective from Koha item type
  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-18248 25.06.2025 25.06.2025 Documentos solicitados