MARC details
| 000 -LEADER |
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| fixed length control field |
02040nam a2200313Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20250625160227.0 |
| 040 ## - CATALOGING SOURCE |
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| Transcribing agency |
CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) |
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| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) |
B-18301 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT |
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| Title |
DNA topoisomerase II? inhibitory and anti-HIV-1 flavones from leaves and twigs of Gardenia carinata. |
| 490 0# - SERIES STATEMENT |
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| Volume/sequential designation |
Fitoterapia, 83(2), p.368-372, 2012 |
| 520 3# - SUMMARY, ETC. |
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| Summary, etc. |
Four new flavones, 5,2?-dihydroxy-7,3?,4?,5?-tetramethoxyflavone (1), 5,2?,5?-trihydroxy-7,3?,4?-trimethoxyflavone (2), 5,7,2?,5?-tetrahydroxy-6,3?,4?-trimethoxyflavone (3)and 5,2?,5?-trihydroxy-6,7,3?,4?-tetramethoxyflavone (4), along with the known 5,3?-dihydroxy-6,7,4?,5?-tetramethoxyflavone (5), 5,7,3?,5?-tetrahydroxy-6,4?-dimethoxyflavone (6), syringaldehyde, vanillic acid and scopoletin were isolated from the leaves and twigs of Gardenia carinata (Rubiaceae). Their structures were determined by spectroscopic methods. Flavone 2 exhibited cytotoxic activity against P-388 and MCF-7 cell lines, while 3, 5 and 6 were active only in P-388 cell line. All active compounds were found to inhibit DNA topoisomerase II? activity, which may be responsible for the observed cytotoxicity. Flavones 1-3, 5 and 6 also exhibited anti-HIV-1 activity in the anti-syncytium assay using ?Tat/revMC99 virus and 1A2 cell line system; 2 was most potent. Only flavones 1 and 6 showed considerably activity against HIV-1 reverse transcriptase. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
GARDENIA CARINATA |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
RUBIACEAE |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
FLAVONES |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
CYTOTOXIC ACTIVITY |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
DNA TOPOISOMERASE II? INHIBITORY ACTIVITY |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
ANTI-HIV-1 ACTIVITY |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Kongkum, N. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Tuchinda, P. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Pohmakotr, M. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Reutrakul, V. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Piyachaturawat, P. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Jariyawat, S. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Napaswad, C. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
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| Uniform Resource Identifier |
<a href="https://drive.google.com/file/d/1Qv4rNea5S2bmzSYrvtbxMgwl9q9qiG5b/view?usp=drivesdk">https://drive.google.com/file/d/1Qv4rNea5S2bmzSYrvtbxMgwl9q9qiG5b/view?usp=drivesdk</a> |
| Public note |
Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Source of classification or shelving scheme |
Clasificación local |
| Koha item type |
Documentos solicitados |
