Effect of D-penicillamine in vitro and in vivo on macrophage phagocytosis. (Record no. 52482)
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| fixed length control field | 02004nam a2200217Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250625162410.0 |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) | |
| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) | B-18330 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT | |
| Title | Effect of D-penicillamine in vitro and in vivo on macrophage phagocytosis. |
| 490 0# - SERIES STATEMENT | |
| Volume/sequential designation | BioChemical Pharmacology, 29(17), p.2273-2278, 1980 |
| 520 3# - SUMMARY, ETC. | |
| Summary, etc. | Preincubation of rat peritoneal macrophages with D-penicillamine increased their uptake of labelled aggregated human gamma globulin ([125I]AHG)without affecting the rate of degradation of the aggregates. Administration of D-penicillamine (50 mg.kg?1. day?1 p.o.)to normal rats resulted in increased uptake of [25I]AHG by peritoneal macrophages after 4 days of treatment, but not after 14 and 28 days of treatment. In contrast, macrophages from rats with adjuvant arthritis treated with D-penicillamine (50 mg.kg?1. day?1 p.o.)exhibited an increased uptake of [125I]AHG throughout the course of the disease. Administration of D-penicillamine in vivo had no effect on the rate of degradation of [125I]AHG by freshly prepared macrophages. Culture for 24 hr in vitro prior to incubation with [125I]AHG led to a decrease in the rate of degradation of the labelled aggregates by macrophages from untreated or D-penicillamine-treated rats and from rats with adjuvant arthritis, but not by macrophages from D-penicillamine-treated adjuvant arthritic rats. It is suggested that D-penicillamine may exert a stimulatory effect on the reticuloendothelial function during chronic inflammatory disease, and that this effect may be mediated via an interaction with the macrophage plasma membrane. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | MACROPHAGE |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | PHAGOCYTOSIS |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Binderup, L. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Bramm, E. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Arrigoni-Martelli, E. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://drive.google.com/file/d/1rRdwR7xRe_SNmMZ5FbDly7vV-2crxJer/view?usp=drivesdk">https://drive.google.com/file/d/1rRdwR7xRe_SNmMZ5FbDly7vV-2crxJer/view?usp=drivesdk</a> |
| Public note | Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Clasificación local |
| Koha item type | Documentos solicitados |
| Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection | Home library | Current library | Shelving location | Date acquired | Total checkouts | Full call number | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Clasificación local | Ref1 | CICY | CICY | Documento préstamo interbibliotecario | 25.06.2025 | B-18330 | 25.06.2025 | 25.06.2025 | Documentos solicitados |