Shotgun metagenome guided exploration of anthropogenically driven resistomic hotspots within Lonar soda lake of India. (Record no. 52621)

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fixed length control field 02425nam a2200301Ia 4500
003 - CONTROL NUMBER IDENTIFIER
control field MX-MdCICY
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250625162413.0
040 ## - CATALOGING SOURCE
Transcribing agency CICY
090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN)
Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-18470
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
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245 10 - TITLE STATEMENT
Title Shotgun metagenome guided exploration of anthropogenically driven resistomic hotspots within Lonar soda lake of India.
490 0# - SERIES STATEMENT
Volume/sequential designation Ecotoxicology and Environmental Safety, 194, p.110443. , 2020
520 3# - SUMMARY, ETC.
Summary, etc. Anthropogenic activities mediated antibiotic resistance genes (ARGs)in the pristine aquatic bodies (lakes)is raising concern worldwide. Long read shotgun sequencing was used to assess taxonomic diversity, distribution of ARGs and metal resistance genes (MRGs)and mobile genetic elements (MGEs)in six sites within hypersaline Lonar soda lake (India)prone to various anthropogenic activities. Proteobacteria and Euryarchaeota were dominant phyla under domain Bacteria and Archaea respectively. Higher abundance of Bacteroidetes was pragmatic at sites 18LN5 and 18LN6. Functional analysis indicated 26 broad-spectrum ARGs types, not reported earlier in this ecosystem. Abundant ARG types identified were multidrug efflux, glycopepetide, bacitracin, tetracycline and aminogylcoside resistance. Sites 18LN1 and 18LN5 depicted 167 and 160 different ARGs subtypes respectively and rpoB2, bcrA, tetA(48), mupA, ompR, patA, vanR and multidrug ABC transporter genes were present in all samples. The rpoB2 gene was dominant in 18LN1, whereas bcrA gene in 18LN2-18LN6 sites. Around 24 MRGs types were detected with higher abundance of arsenic in 18LN1 and copper in 18LN2-18LN6, signifying metal contamination linked to MRGs. The bacterial taxa Pseudomonas, Thioalkalivibrio, Burkholderia, Clostridium, Paenibacillus, Bacillus and Streptomyces were significantly associated with ARGs. This study highlights the resistomic hotspots in the lake for deploying policies for conservation efforts.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element LONAR LAKE
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element DIVERSITY
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element NANOPORE SEQUENCING
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element ARGS
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element MRGS
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element MGES
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Chakraborty, J.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Sapkale, V.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Rajput, V.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Shah, M.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Kamble, S.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Dharne, M.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1n0DTEJpThUSJJZHdnQntHCrs5AOKZPjf/view?usp=drivesdk">https://drive.google.com/file/d/1n0DTEJpThUSJJZHdnQntHCrs5AOKZPjf/view?usp=drivesdk</a>
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Source of classification or shelving scheme Clasificación local
Koha item type Documentos solicitados
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-18470 25.06.2025 25.06.2025 Documentos solicitados