Corrigendum: fabrication and in vitro characterization of bioactive glass composite scaffolds for bone regeneration (2013 Biofabrication 5 045005). (Record no. 52769)

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control field 20250625162416.0
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Transcribing agency CICY
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Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-18622
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Title Corrigendum: fabrication and in vitro characterization of bioactive glass composite scaffolds for bone regeneration (2013 Biofabrication 5 045005).
490 0# - SERIES STATEMENT
Volume/sequential designation Biofabrication, 6(2), p.029501., 2014
520 3# - SUMMARY, ETC.
Summary, etc. Here we fabricate and characterize bioactive composite scaffolds for bone tissue engineering applications. 45S5 Bioglass® (45S5)or strontium-substituted bioactive glass (SrBG)were incorporated into polycaprolactone (PCL)and fabricated into 3D bioactive composite scaffolds utilizing additive manufacturing technology. We show that composite scaffolds (PCL/45S5 and PCL/SrBG)can be reproducibly manufactured with a scaffold morphology highly resembling that of PCL scaffolds. Additionally, micro-CT analysis reveals BG particles were homogeneously distributed throughout the scaffolds. Mechanical data suggested that PCL/45S5 and PCL/SrBG composite scaffolds have higher compressive Young's modulus compared to PCL scaffolds at similar porosity (~75 percent). After 1 day in accelerated degradation conditions using 5M NaOH, PCL/SrBG, PCL/45S5 and PCL lost 48.6 ± 3.8 percent, 12.1 ± 1 percent and 1.6 ± 1 percent of the original mass, respectively. In vitro studies were conducted using MC3T3 cells under normal and osteogenic conditions. All scaffolds were shown to be non-cytotoxic, and supported cell attachment and proliferation. Our results also indicate that the inclusion of bioactive glass (BG)promotes precipitation of calcium phosphate on the scaffold surfaces which leads to earlier cell differentiation and matrix mineralization when compared to PCL scaffolds. However, as indicated by alkaline phosphatase activity, no significant difference in osteoblast differentiation was found between PCL/45S5 and PCL/SrBG scaffolds. These results suggest that PCL/45S5 and PCL/SrBG composite scaffolds show potential as next generation bone scaffolds.
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Topical term or geographic name entry element BONE REGENERATION
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Personal name Poh, P. S.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Hutmacher, D. W.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Stevens, M. M.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Woodruff, M. A.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1tkojP9ptk-tm2A6LIETwEPlvP5k5BrgD/view?usp=drivesdk">https://drive.google.com/file/d/1tkojP9ptk-tm2A6LIETwEPlvP5k5BrgD/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-18622 25.06.2025 25.06.2025 Documentos solicitados