MARC details
| 000 -LEADER |
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| fixed length control field |
02434nam a2200337Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20250625162417.0 |
| 040 ## - CATALOGING SOURCE |
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| Transcribing agency |
CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) |
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| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) |
B-18703 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT |
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| Title |
Inducing new bioactive metabolites production from coculture of Pestalotiopsis sp. and Penicillium bialowiezense |
| 490 0# - SERIES STATEMENT |
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| Volume/sequential designation |
Bioorganic Chemistry, 110, p.104826, 2021 |
| 520 3# - SUMMARY, ETC. |
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| Summary, etc. |
Coculturing two or more fungi is a useful strategy to awaken the silent genes to produce structurally diverse and bioactive natural products. Through the coculture of Pestalotiopsis sp. and Penicillium bialowiezense, six new isoprenylated chromane derivatives, including two pairs of enantiomeric ones (1a/1b-2a/2b)and two optical pure ones (3-4), two new isoprenylated phenol glucoside derivatives (6-7), as well as eight known structural analogues (5 and 8-14), were obtained. The structures of these new compounds were characterized by NMR spectroscopy, single-crystal X-ray crystallography, and ECD calculation. The ? 10,11 double bond of pestaloficin D (5)was revised to E-configurated based on the extensive spectroscopic analyses. Compounds 1a/1b and 2a/2b were the first examples of enantiomeric isoprenylated chromane derivatives, which were successfully separated by chiral HPLC. Additionally, all the isolated compounds were evaluated for the in vitro ß-glucuronidase (GUS)and butyrylcholinesterase (BChE)inhibitory activities. Compounds 1a and 1b showed significant ß-glucuronidase inhibitory potency with IC 50 values of 7.6 and 10.3 µM, respectively. Compound 14 exhibited moderate BChE inhibitory activity with an IC 50 value of 21.3 µM. In addition, the structure-enzyme inhibitory activity relationship of compounds 1-14 is discussed. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
PESTALOTIOPSIS SP |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
PENICILLIUM BIALOWIEZENSE |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
COCULTURE |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
STRUCTURAL ELUCIDATION |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
GUS AND BCHE INHIBITORY ACTIVITIES |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Li, Fengli |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Yan, Shan |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Huang, Zhangyan |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Gao, Weixi |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Zhang, Sitian |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Mo, Shuyuan |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Lin, Shuang |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Lin, Shuang |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Hu, Zhengxi |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Zhang, Yonghui |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
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| Uniform Resource Identifier |
<a href="https://drive.google.com/file/d/1hm__oquOh1LaLHOyQ7z7cXkngeP9dPeh/view?usp=drivesdk">https://drive.google.com/file/d/1hm__oquOh1LaLHOyQ7z7cXkngeP9dPeh/view?usp=drivesdk</a> |
| Public note |
Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Source of classification or shelving scheme |
Clasificación local |
| Koha item type |
Documentos solicitados |
