o-Vanillin, a promising antifungal agent, inhibits Aspergillus by disrupting the integrity of cell walls and cell membranes (Record no. 52855)

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control field MX-MdCICY
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250625162417.0
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Transcribing agency CICY
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Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-18709
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245 10 - TITLE STATEMENT
Title o-Vanillin, a promising antifungal agent, inhibits Aspergillus by disrupting the integrity of cell walls and cell membranes
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Volume/sequential designation Applied MicroBiology and Biotechnology, https://doi.org/10.1007/s00253-021-11371-2, 2021
520 3# - SUMMARY, ETC.
Summary, etc. o-Vanillin is a natural product that has been widely applied in the food and pharmaceutical industries. In this study, we determined thato-vanillin can strongly inhibit the growth ofAspergillus flavusmycelia. However, the inhibition mechanism ofo-vanillin is still elusive. The ultrastructural morphology of mycelia was injured, and the cell walls were destroyed. The OHfunctional groups on cell walls were altered, and the content of protein in mycelial cell walls was reduced byo-vanillin. Thecontent ofß-1,3-glucan in cell walls was significantly (P< 0.05)reduced byo-vanillin in a dose-dependent manner, while chitin was not markedly affected. Moreover,o-vanillin led to an increase in the permeability of cell membranes. o-Vanillin also exhibited a promising antifungal effect on contaminated corn kernels. Therefore,o-vanillin inhibited the growth of mycelia by disrupting the integrity of cell walls and cell membranes. This study not only sheds light on the antifungal mechanism ofovanillin but also indicates that it is a promising agent for the control ofA. flavusinfection. Key points
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Li, Qian
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Zhu, Xiaoman
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Xie, Yanli
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Zhong, Yue
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1tbfgYvh0pg1rq-VLfFcmogoYM5L1QZmb/view?usp=drivesdk">https://drive.google.com/file/d/1tbfgYvh0pg1rq-VLfFcmogoYM5L1QZmb/view?usp=drivesdk</a>
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Source of classification or shelving scheme Clasificación local
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-18709 25.06.2025 25.06.2025 Documentos solicitados