Thirty Years of HDAC Inhibitors: 2020 Insight and Hindsight (Record no. 52868)

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fixed length control field 01151nam a2200193Ia 4500
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control field MX-MdCICY
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control field 20250625162417.0
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Transcribing agency CICY
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Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-18722
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Title Thirty Years of HDAC Inhibitors: 2020 Insight and Hindsight
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Volume/sequential designation J. Med. Chem, 63, p.12460-12484, 2020
520 3# - SUMMARY, ETC.
Summary, etc. It is now 30 years since the first report of a potent zincdependent histone deacetylase (HDAC)inhibitor appeared. Since then, five HDAC inhibitors have received regulatory approval for cancer chemotherapy while many others are in clinical development for oncology as well as other therapeutic indications. This Perspective reviews the biological and medicinal chemistry advances over the past 3 decades with an emphasis on the design of selective inhibitors that discriminate between the 11 human HDAC isoforms.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Ho, Terence C. S.
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Personal name Chan, Alex H. Y.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Ganesan, A.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1G1JalsFr3YBxBV-Tfd-3Ewr5R8ZHMwph/view?usp=drivesdk">https://drive.google.com/file/d/1G1JalsFr3YBxBV-Tfd-3Ewr5R8ZHMwph/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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Source of classification or shelving scheme Clasificación local
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-18722 25.06.2025 25.06.2025 Documentos solicitados