MARC details
| 000 -LEADER |
|---|
| fixed length control field |
02717nam a2200289Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
|---|
| control field |
MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
|---|
| control field |
20250625162418.0 |
| 040 ## - CATALOGING SOURCE |
|---|
| Transcribing agency |
CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) |
|---|
| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) |
B-18736 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT |
|---|
| Title |
Neurobehavioral and toxicological effects of an aqueous extract ofTurnera diffusaWilld (Turneraceae)in mice |
| 490 0# - SERIES STATEMENT |
|---|
| Volume/sequential designation |
Journal of EthnoPharmacology, 236, p.50-62, 2019 |
| 520 3# - SUMMARY, ETC. |
|---|
| Summary, etc. |
Aims:To explore the antidepressant- and anxiolytic-like effects of an aqueous extract ofTurnera diffusaWilld (Turneraceae)and to explore its possible toxic side effects on behavior, target organ function, and spermatic quality. Materials and methods:Acute effects of aT. diffusaaqueous extract were evaluated in adult male mice with the plus-maze, forced swimming and open field tests to identify the possible anxiolytic, antidepressant and stimulant effects of this extract. Effects ofT. diffusaaqueous extract were further investigated through two approaches. a)Male and female adult mice receiving a 28-day treatment were evaluated in a neurobehavioral test battery; later, changes in their biochemical parameters and in target organ morphology were analyzed. b)In young adult (16-weeks old)and mature (46-weeks old)males, spermatic quality and testes morphology during a complete spermatogenesis cycle were analyzed after a 35-day treatment. Results: T. diffusaaqueous extract induced remarkable anxiolytic- and antidepressant-like effects without affecting locomotor activity. This extract did not elicit behavioral signs of neural side effects, a sex-dependent reduction in body weight gain was produced without affecting functional parameters or the morphology of target organs. The highest dose improved cellular turnover in the testes of mature mice. Conclusion: T. diffusaaqueous extract induced a clear anxiolytic-like effect, and for the first time, we reported an antidepressant effect. Clinical potential or even intake ofT. diffusain the context of traditional medicine can be supported by its efficacy to positively modulate behavior and its safety for a wide range of doses. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
T. DIFFUSA |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
ANTIDEPRESSANT |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
ANXIOLYTIC |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
ADAPTOGENIC |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
TESTICULAR FUNCTION SPERMATIC INTEGRIT |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Dorantes-Barrón, Ana María |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Vigueras Villaseñor, Rosa María |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Mayagoitia-Novales, Lilian |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Martínez-Mota, Lucía |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Gutiérrez-Pérez, Oscar |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Estrada-Reyes, Rosa |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Uniform Resource Identifier |
<a href="https://drive.google.com/file/d/1aUqBmJAZ9liRe3pyMpaWPISdkeReLh_e/view?usp=drivesdk">https://drive.google.com/file/d/1aUqBmJAZ9liRe3pyMpaWPISdkeReLh_e/view?usp=drivesdk</a> |
| Public note |
Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
Clasificación local |
| Koha item type |
Documentos solicitados |
