Integration of lipidomic and transcriptomic profiles reveals novel genes and regulatory mechanisms of Schizochytrium sp. in response to salt stress (Record no. 53058)
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| 000 -LEADER | |
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| fixed length control field | 02188nam a2200313Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250625162421.0 |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) | |
| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) | B-18915 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT | |
| Title | Integration of lipidomic and transcriptomic profiles reveals novel genes and regulatory mechanisms of Schizochytrium sp. in response to salt stress |
| 490 0# - SERIES STATEMENT | |
| Volume/sequential designation | Bioresource Technology, 294, p.122231, 2019 |
| 520 3# - SUMMARY, ETC. | |
| Summary, etc. | In this study, the effects of salt stress on the physiological, lipidomic and transcriptomic profiles of halophilic microalga Schizochytrium sp. were investigated. In general, Schizochytrium sp. could survive under high osmotic fermentation medium containing 30 g/L NaCl, and showed a significant increase in C14:0 percentage in total fatty acids. In lipidomic analysis, C14:0 was specifically enriched in phosphatidylcholine (PC), and membrane phospholipids participated in the salt stress response mostly. Specially, one novel signal lipid N-acylphosphatidylethanolamine (NAPE)(18:0/20:3/14:0)was upregulated significantly. Transcriptomic analysis revealed glycerol-3-phosphate acyltransferase (GPAT)and phospholipase ABHD3 (PLABDH3)were involved in C14:0 metabolism and NAPE biosynthesis. Signalling pathways they mediated were activated as evident by high expression level of Myristoyl-CoA: protein N-myristoyltransferase (NMT)and NAPE-hydrolyzing PLD (NAPE-PLD). This study gives us an insight in specific responses to salt stress in Schizochytrium sp. and provides a considerable proportion of novel genes that could commendably be used for engineering modification. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | ACYLTRANSFERAS |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | HALOPHILE |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | LIPIDOMICS |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | N-ACYLPHOSPHATIDYLETHANOLAMINE |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | SCHIZOCHYTRIUM SP. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | TRANSCRIPTOMICS |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Jiang, J. Y. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Zhu, S. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Zhang, Y. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Sun, X. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hu, X. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Huang, H. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ren, L. J. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://drive.google.com/file/d/1AM-Y7UXgGrKF2SHHDDGJ5EzgeOAXpBKo/view?usp=drivesdk">https://drive.google.com/file/d/1AM-Y7UXgGrKF2SHHDDGJ5EzgeOAXpBKo/view?usp=drivesdk</a> |
| Public note | Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Clasificación local |
| Koha item type | Documentos solicitados |
| Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection | Home library | Current library | Shelving location | Date acquired | Total checkouts | Full call number | Date last seen | Price effective from | Koha item type |
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| Clasificación local | Ref1 | CICY | CICY | Documento préstamo interbibliotecario | 25.06.2025 | B-18915 | 25.06.2025 | 25.06.2025 | Documentos solicitados |