Design of psyllium-g-poly(acrylic acid-co-sodium acrylate)/cloisite 10A semi-IPN nanocomposite hydrogel and its mechanical, rheological and controlled drug release behaviour (Record no. 53080)

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control field MX-MdCICY
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control field 20250625162421.0
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Transcribing agency CICY
090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN)
Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-18937
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245 10 - TITLE STATEMENT
Title Design of psyllium-g-poly(acrylic acid-co-sodium acrylate)/cloisite 10A semi-IPN nanocomposite hydrogel and its mechanical, rheological and controlled drug release behaviour
490 0# - SERIES STATEMENT
Volume/sequential designation International Journal of Biological Macromolecules, 111, p.983-998, 2018
520 3# - SUMMARY, ETC.
Summary, etc. Soft biomaterials derived from polysaccharides are generally suffers from lack of mechanical robustness and instability. The naturally occurring highly abundance low cost polysaccharide has immense aspect as biomaterial after functionalization which can be designed as stretchable and rubber-like elastic with reversible ductility. A highly swellable, stretchable, low creep, non-cytotoxic nanocomposite hydrogel has been fabricated by simple one-pot Michael type covalent grafting of acrylic acid based copolymer onto psyllium biomacromolecular chian by free radical gelation technique. The fabricated hydrogel was rheologically tested which implies its viscoelastic and thixotropic like features. The porous morphology of the hydrogel was confirmed by scanning electron micrograph. The cryo-transmission electron micrograph shows the random dispersion of the nanoclay (cloisite 10A)tactoids in exfoliated as well intercalated forms. These random distributions of clay nanosheets also enhance the mechanical toughness and reversible ductility of the hydrogels which was also supported by the mechanical and loading-unloading cycle measurement. Nonetheless, the nanocomposite hydrogel was non-cytotoxic against human cell-line (human osteosarcoma)and shows good cell attachment of live cells in a 5-day 'live-dead' assay with almost negligible quantity of cell death. These attributes can promote this material as a soft biomaterial for controlled release device with mechanical robustness and rubber-like elasticity.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element PSYLLIUM POLYSACCHARIDE
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element CLOISITE 10A
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element STRETCHABLE BIOMACROMOLECULE
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Ganguly, S.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Mondal, S.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Das, P.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Bhawal, P.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Maity, P. P.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Ghosh, S.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Das, N. C.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1lZwjlgJrSUStld2jQBPDl7JeXD_bbubQ/view?usp=drivesdk">https://drive.google.com/file/d/1lZwjlgJrSUStld2jQBPDl7JeXD_bbubQ/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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Source of classification or shelving scheme Clasificación local
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-18937 25.06.2025 25.06.2025 Documentos solicitados