Identification, analysis, and modeling of the YUCCA protein family genome-wide in Coffea canephora (Record no. 53114)

MARC details
000 -LEADER
fixed length control field 02519nam a2200289Ia 4500
003 - CONTROL NUMBER IDENTIFIER
control field MX-MdCICY
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250625162422.0
040 ## - CATALOGING SOURCE
Transcribing agency CICY
090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN)
Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-18972
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245 10 - TITLE STATEMENT
Title Identification, analysis, and modeling of the YUCCA protein family genome-wide in Coffea canephora
490 0# - SERIES STATEMENT
Volume/sequential designation Proteins: Structure, Function, and Bioinformatics, 90(4), p.1005-1024, 2022
520 3# - SUMMARY, ETC.
Summary, etc. Auxin is involved in almost every aspect of plant growth and development, from embryogenesis to senescence. Indole-3-acetic acid (IAA)is the main known natural auxin that is synthesized by enzymes tryptophan aminotransferase of arabidopsis (TAA)and YUCCA (YUC)of the flavin-containing monooxygenases family (FMO)from one of the tryptophan-dependent pathways. Genome-wide identification and comprehensive analysis of the YUC-protein family have been conducted in Coffea canephora in the present study. A total of 10 members CcYUC gene family were identified in C. canephora. Phylogenetic analysis revealed that the CcYUC protein family is evolutionarily conserved, and they consist of four groups. In contrast, bioinformatic analysis predicted a hydrophobic transmembrane helix (TMH)for one CcYUC (YUC10)member only. Isoelectric point (pI), molecular mass (Ms), signal peptide, subcellular localization, and phosphorylation sites were predicted for CcYUC proteins. YUC enzymes require the prosthetic group flavin adenine dinucleotide (FAD)and the cofactor nicotinamide adenine dinucleotide phosphate (NADPH)for their enzymatic activity. Therefore, we include the molecular docking for CcYUC2-FAD-NADPH-IPyA and yucasin, which is a specific inhibitor for YUC activity. The docking results showed FAD and NADPH binding at the big and small domain sites, respectively, in CcYUC2. IPyA binds very close to FAD along the big domain, and yucasin competes for the same site as IPA, blocking IAA production. Furthermore, in silico point mutations affect the stability of the CcYUC2-4 proteins.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element AUXIN
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element COFFEA CANEPHORA
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element DOCKING
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element FMO
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element IPYA
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element YUCASIN
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element YUCCA
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Uc-Chuc, M. A.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Kú-González, Á. F.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Jiménez-Ramírez, I. A.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Loyola-Vargas, V. M.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/10SsYgcihT98sLXyDW0qFOuVxzr4lc1Iq/view?usp=drivesdk">https://drive.google.com/file/d/10SsYgcihT98sLXyDW0qFOuVxzr4lc1Iq/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Clasificación local
Koha item type Documentos solicitados
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-18972 25.06.2025 25.06.2025 Documentos solicitados