MARC details
| 000 -LEADER |
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| fixed length control field |
02136nam a2200301Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20250625162424.0 |
| 040 ## - CATALOGING SOURCE |
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| Transcribing agency |
CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) |
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| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) |
B-19057 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT |
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| Title |
Transcriptomic and metabolomic analyses reveal antibacterial mechanism of astringent persimmon tannin against Methicillin-resistant Staphylococcus aureus isolated from pork |
| 490 0# - SERIES STATEMENT |
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| Volume/sequential designation |
Food Chemistry, 309, p.125692, 2020 |
| 520 3# - SUMMARY, ETC. |
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| Summary, etc. |
Persimmon tannin (PT)exhibits antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA)isolated from retail pork. The involved molecular mechanisms were investigated for the first time using transcriptome and metabolome in this study. Results showed that subinhibitory concentration of PT (0.5 mg/ml)induced significant changes in MRSA at both transcriptional and metabolic levels, as 370 genes and 19 metabolites were differentially expressed. Bioinformatic analysis revealed that the varying genes and metabolites were mainly involved in pathways of membrane transport, amino acids, carbohydrate, and energy metabolism. The highlighted changes were those related to osmotic regulation, intracellular pH regulation, amino acid synthesis and metabolism, glycolysis, TCA cycle and iron metabolism, suggesting the multifaceted effects including cell membrane damage, amino acids limitation, energy metabolism disorder and iron deprivation induced by PT. The results provided insight into the anti-MRSA mechanism of PT, which is useful for PT's development and application in food safety. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
ANTIBACTERIAL MECHANISM |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
FOODBORNE METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
METABOLOME |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
PERSIMMON TANNIN |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
TRANSCRIPTOME |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Liu, M. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Feng, M. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Yang, K. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Cao, Y. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Zhang, J. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Xu, J. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Fan, M. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
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| Uniform Resource Identifier |
<a href="https://drive.google.com/file/d/1t2JQSR-zhlB5dcTDb_sCbsJcjrEt8wbg/view?usp=drivesdk">https://drive.google.com/file/d/1t2JQSR-zhlB5dcTDb_sCbsJcjrEt8wbg/view?usp=drivesdk</a> |
| Public note |
Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Source of classification or shelving scheme |
Clasificación local |
| Koha item type |
Documentos solicitados |
