Structural and mechanistic aspects of carotenoid cleavage dioxygenases (CCDs) (Record no. 53434)

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fixed length control field 01989nam a2200253Ia 4500
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control field MX-MdCICY
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control field 20250625162428.0
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Transcribing agency CICY
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Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-19297
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Title Structural and mechanistic aspects of carotenoid cleavage dioxygenases (CCDs)
490 0# - SERIES STATEMENT
Volume/sequential designation Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids, 1865(11), p.158590, 2020
520 3# - SUMMARY, ETC.
Summary, etc. Carotenoid cleavage dioxygenases (CCDs)comprise a superfamily of mononuclear non-heme iron proteins that catalyze the oxygenolytic fission of alkene bonds in carotenoids to generate apocarotenoid products. Some of these enzymes exhibit additional activities such as carbon skeleton rearrangement and trans-cis isomerization. The group also includes a subfamily of enzymes that split the interphenyl alkene bond in molecules such as resveratrol and lignostilbene. CCDs are involved in numerous biological processes ranging from production of light-sensing chromophores to degradation of lignin derivatives in pulping waste sludge. These enzymes exhibit unique features that distinguish them from other families of non-heme iron enzymes. The distinctive properties and biological importance of CCDs have stimulated interest in their modes of catalysis. Recent structural, spectroscopic, and computational studies have helped clarify mechanistic aspects of CCD catalysis. Here, we review these findings emphasizing common and unique properties of CCDs that enable their variable substrate specificity and regioselectivity.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element NON-HEME IRON
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Topical term or geographic name entry element BETA-PROPELLER
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Topical term or geographic name entry element NITRIC OXIDE
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element RESVERATROL
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element DIOXETANE
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element MONOTOPIC MEMBRANE PROTEIN
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Daruwalla, A.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Kiser, P. D.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1v9oymx1zU5X7_IOXRlj5HRVb3G4S9HxU/view?usp=drivesdk">https://drive.google.com/file/d/1v9oymx1zU5X7_IOXRlj5HRVb3G4S9HxU/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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Source of classification or shelving scheme Clasificación local
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-19297 25.06.2025 25.06.2025 Documentos solicitados