MARC details
| 000 -LEADER |
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| fixed length control field |
02375nam a2200277Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20250625162429.0 |
| 040 ## - CATALOGING SOURCE |
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| Transcribing agency |
CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) |
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| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) |
B-19358 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT |
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| Title |
Anti-phytopathogenic activity and the possible mechanisms of action of isoquinoline alkaloid sanguinarine |
| 490 0# - SERIES STATEMENT |
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| Volume/sequential designation |
Pesticide BioChemistry and physiology, 159, p.51-58, 2019 |
| 520 3# - SUMMARY, ETC. |
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| Summary, etc. |
Isoquinoline alkaloids possess broad pharmacological activities. In this study, the antifungal activity of twelve isoquinoline alkaloids, including berberine (1), jatrorrhizine (2), coptisine (3), corydaline (4), tetrahydroberberine (5), chelidonine (6), dihydrosanguinarine (7), chelerythrine (8), sanguinarine (9), palmatine (10), tetrahydropalmatine (11)and columbamine (12)were evaluated against eight plant pathogenic fungi in vitro. All the tested compounds showed varying degrees of inhibition against the eight tested plant fungi. Among them, sanguinarine exhibited high antifungal activity (EC50 ranging from 6.96-59.36??g/mL). It displayed the best inhibitory activity against Magnaporthe oryzae (EC50?=?6.96??g/mL), compared with azoxystrobin (EC50?=?12.04??g/mL), and significantly suppressed spore germination of M. oryzae with the inhibition rate reaching 100 percent (50??g/mL). The optical microscopy and scanning electron microscopy observations revealed that after treating M. oryzae mycelia with sanguinarine at 10??g/mL, the mycelia appeared curved, collapsed and the cell membrane integrity was eventually damaged. Furthermore, the reactive oxygen species production, mitochondrial membrane potential and nuclear morphometry of mycelia had been changed, and the membrane function and cell proliferation of mycelia were destroyed. These results will enrich our insights into action mechanisms of antifungal activity of sanguinarine against M. oryzae. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
ISOQUINOLINE ALKALOIDS |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
SANGUINARINE |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
FUNGICIDAL ACTIVITY |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Zhao, Z. M. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Shang, X. F. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Lawoe, R. K. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Liu, Y. Q. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Zhou, R. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Sun, Y. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Yang, C. J. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
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| Uniform Resource Identifier |
<a href="https://drive.google.com/file/d/1dMbJ_RPxEcx_6xgqJC-J864RPPTToQjV/view?usp=drivesdk">https://drive.google.com/file/d/1dMbJ_RPxEcx_6xgqJC-J864RPPTToQjV/view?usp=drivesdk</a> |
| Public note |
Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Source of classification or shelving scheme |
Clasificación local |
| Koha item type |
Documentos solicitados |
