Generation of microalga Chlamydomonas reinhardtii expressing VP28 protein as oral vaccine candidate for shrimps against White Spot Syndrome Virus (WSSV)infection (Record no. 53532)

MARC details
000 -LEADER
fixed length control field 02267nam a2200313Ia 4500
003 - CONTROL NUMBER IDENTIFIER
control field MX-MdCICY
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250625162430.0
040 ## - CATALOGING SOURCE
Transcribing agency CICY
090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN)
Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-19403
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 250602s9999 xx |||||s2 |||| ||und|d
245 10 - TITLE STATEMENT
Title Generation of microalga Chlamydomonas reinhardtii expressing VP28 protein as oral vaccine candidate for shrimps against White Spot Syndrome Virus (WSSV)infection
490 0# - SERIES STATEMENT
Volume/sequential designation Aquaculture, 540, p.736737, 2021
520 3# - SUMMARY, ETC.
Summary, etc. White Spot Syndrome Virus (WSSV)is a major cause of mortality in shrimp cultivation on farms all around the world. The serious monetary losses related with its occurrence in susceptible shrimps and the limitations of current methods used to treat WSSV disease in Vietnam, highlight the need for new methods to prevent and to manage the disease. The current study investigates the possibility of expressing the VP28 protein of WSSV from the nucleus of Chlamydomonas reinhardtii for WSSV control. The VP28 protein of WSSV was successfully expressed in C. reinhardtii as confirmed by Western blot analysis and RT-PCR. The immunological parameters analyzed in shrimp administered with 4 mg of dried algae (~ 6 × 10? cells)/1 g shrimp showed a high-level expression of lysosome (LSZ), anti-lipopolysaccharide factor (ALF), superoxide dismutase (SOD)and prophenoloxidase (proPO)compared to the control group. The result of oral administration experiments indicated that vaccinated shrimp survived up to 70 percent of the time as opposed to control group with 100 percent mortality. Taken together, the result indicated that recombinant C. reinhardtii expressing VP28 has a potential utility as an oral vaccine candidate against WSSV.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element CHLAMYDOMANAS REINHARDTII
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element NUCLEAR
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element ORAL VACCINE
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element RECOMBINANT PROTEIN
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element SHRIMP
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element WHITE SPOT SYNDROME VIRUS
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Lanh, P. T.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Nguyen, H. M.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Duong, B. T. T.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Hoa, N. T.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Tam, L. T.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Thu, H. T.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Van Quyen, D.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1qrL-7b-jS0p8obgBRPrT0vlucuaFAvfh/view?usp=drivesdk">https://drive.google.com/file/d/1qrL-7b-jS0p8obgBRPrT0vlucuaFAvfh/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Clasificación local
Koha item type Documentos solicitados
Holdings
Lost status Source of classification or shelving scheme Damaged status Not for loan Collection Home library Current library Shelving location Date acquired Total checkouts Full call number Date last seen Price effective from Koha item type
  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-19403 25.06.2025 25.06.2025 Documentos solicitados