Antibacterial and antibiofilm activities of Mayan medicinal plants against Methicillin-susceptible and-resistant strains of Staphylococcus aureus (Record no. 53535)

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control field 20250625162430.0
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Transcribing agency CICY
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Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-19406
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Title Antibacterial and antibiofilm activities of Mayan medicinal plants against Methicillin-susceptible and-resistant strains of Staphylococcus aureus
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Volume/sequential designation Journal of EthnoPharmacology, 279, p.114369, 2021
520 3# - SUMMARY, ETC.
Summary, etc. Ethnopharmacological relevance: Several medicinal plants are used in Mayan Traditional Medicine to treat skin, urinary, respiratory, and gastrointestinal infectious diseases. However, scientific studies that have supported the bioactivity of these Mayan medicinal plants are limited. Aim of the study: To assess the in-vitro anti-Staphylococcus aureus growth and biofilm-formation activities of 15 Mayan medicinal plants that were selected based on their traditional uses for the treatment of infectious diseases. Materials and methods: Mayan medicinal plants used traditionally to treat infectious diseases were preselected. For each part of the plants, four extracts were prepared with different solvents (water, n-hexane, ethyl acetate, and methanol). These were tested against two reference strains: a Methicillin-susceptible and -resistant S. aureus, and two clinical isolates, including a susceptible and multidrug-resistant S. aureus using a Resazurin Microtiter Assay. In addition, the plant extracts were evaluated in biofilm-formation S. aureus by means of the crystal violet method. Results: A total of 120 extracts from 15 Mayan medicinal plant species belonging to 12 different families were selected according their ethnopharmacological uses to treat infectious diseases. Among the selected plant species, 26 extracts obtained from eight medicinal Mayan plants exhibited significant anti-S. aureus against the four strains tested. The most active extracts were the Aq (aqueous)leaf extract of Krugiodendron ferreum (Minimal Inhibitory Concentration [MIC]= 125-250 ?g/mL), the MeOH bark extracts of Matayba oppositifolia, Clusia flava, Gymnopodium floribundum, the MeOH leaf extract of Spondias purpurea with MIC values of 250 ?g/mL, and the MeOH leaf and Aq bark extracts of K. ferreum (MIC = 250-500 ?g/mL). Among the active extracts, 12 exhibited a bactericidal effect on S. aureus strains (Minimal Bactericidal Concentration [MBC]= 250-1000 ?g/mL). Forty extracts from 13 plants have an effect on the anti-formation of biofilm, the most active were the MeOH leaf extract of M. oppositifolia (one-half Minimal Inhibitory Concentration [IC50]= 10.4 ?g/mL)and the MeOH (IC50 = 17.7 ?g/mL)and Hex (18.2 ?g/mL)leaf extracts from S. purpurea. Conclusion: Aqueous and organic extracts from Mayan medicinal plants showed bactericidal and anti-biofilm activities even against drug-resistant S. aureus strains. The present study supports the traditional usage of some plants employed in Mayan medicine for illnesses such as skin, gastrointestinal, and urinary infections and suggest that these plants could be a good source of antibacterial phytochemicals.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element MAYAN MEDICINAL PLANTS
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element TRADITIONAL MEDICINE
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element ANTIMICROBIAL ACTIVITY
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element ANTIBIOFILM ACTIVITY
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Uc-Cachón, A. H.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Dzul-Beh, A.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Palma-Pech, G. A.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Jiménez-Delgadillo, B.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Flores-Guido, J. S.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Gracida-Osorno, C.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Molina-Salinas, G. M.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1kBttDJCq8fqVfVosEFPOxemVhgoq2GOW/view?usp=drivesdk">https://drive.google.com/file/d/1kBttDJCq8fqVfVosEFPOxemVhgoq2GOW/view?usp=drivesdk</a>
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Source of classification or shelving scheme Clasificación local
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-19406 25.06.2025 25.06.2025 Documentos solicitados