MARC details
| 000 -LEADER |
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| fixed length control field |
02448nam a2200289Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20250625162431.0 |
| 040 ## - CATALOGING SOURCE |
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| Transcribing agency |
CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) |
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| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) |
B-19485 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT |
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| Title |
Phytochemical, Chemotaxonomic and Bioinformatics Study on Laportea bulbifera (Urticaceae) |
| 490 0# - SERIES STATEMENT |
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| Volume/sequential designation |
Chemistry & BioDiversity, doi.org/10.1002/cbdv.202200070, 2022 |
| 520 3# - SUMMARY, ETC. |
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| Summary, etc. |
Phytochemical investigation of the aerial part of Laportea bulbifera (Siebold & Zucc.)Wedd. (L. bulbifera)showed the isolation of seventeen compounds, including five flavonoids (1-4 and 6), one terpenoid (5), five phenolic acids (7-11), one coumarin (12), two steroids (13-14), and three alkaloids (15-17). Structure elucidations of these compounds were performed on the basis of extensive NMR experiments and compared with the published data in the references. It is remarkable that compounds (3-5)were firstly isolated from the Urticaceae family, compounds (3-8, 11 and 15-17)were firstly obtained from genus Laportea. Furthermore, the result of the chemotaxonomic significance discussion showed that compounds (2-4)may can be served as compound fingerprints to distinguish between species of L. bulbifera and genus Urtica, and what' more, we proposed a bold conjecture that isoflavones can distinguish between species of L. bulbifera and genus Urtica. At the same time, the molecular docking method was used to evaluate the inhibitory effect of these compounds on human steroid 5?-reductase 2 (SRD5?2). The results showed that compounds (1-4 and 6)had better expected effects than the positive drug finasteride can by effectively binding to the active sites of SRD5?2. This study assisted in the future phytochemical and chemotaxonomic research on genus Laportea. Simultaneously, this research provided the theoretical evidence for the application of L. bulbifera in treating benign prostatic hyperplasia (BPH). |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
BENIGN PROSTATIC HYPERPLASIA (BPH) |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
L. BULBIFERA |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
CHEMICAL CONSTITUENTS |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
CHEMOTAXONOMIC SIGNIFICANCE |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
ISOFLAVONES |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Lu, X. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Zhao, Y. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Li, B. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Feng, W. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Qi, J. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Feng, B. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
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| Uniform Resource Identifier |
<a href="https://drive.google.com/file/d/1QtuJJt2Cxdgu-hlA-j8euapz84kCieGO/view?usp=drivesdk">https://drive.google.com/file/d/1QtuJJt2Cxdgu-hlA-j8euapz84kCieGO/view?usp=drivesdk</a> |
| Public note |
Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Source of classification or shelving scheme |
Clasificación local |
| Koha item type |
Documentos solicitados |
