Established tools and emerging trends for the production of recombinant proteins and metabolites in Pichia pastoris (Record no. 53693)

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fixed length control field 01742nam a2200265Ia 4500
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control field MX-MdCICY
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control field 20250625162433.0
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Transcribing agency CICY
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Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-19569
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Title Established tools and emerging trends for the production of recombinant proteins and metabolites in Pichia pastoris
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Volume/sequential designation Essays in BioChemistry, 65(2), p.293-307, 2021
520 3# - SUMMARY, ETC.
Summary, etc. Besides bakers' yeast, the methylotrophic yeast Komagataella phaffii (also known as Pichia pastoris)has been developed into the most popular yeast cell factory for the production of heterologous proteins. Strong promoters, stable genetic constructs and a growing collection of freely available strains, tools and protocols have boosted this development equally as thorough genetic and cell biological characterization. This review provides an overview of state-of-the-art tools and techniques for working with P. pastoris, as well as guidelines for the production of recombinant proteins with a focus on small-scale production for biochemical studies and protein characterization. The growing applications of P. pastoris for in vivo biotransformation and metabolic pathway engineering for the production of bulk and specialty chemicals are highlighted as well.
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Topical term or geographic name entry element METABOLIC ENGINEERING
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Topical term or geographic name entry element RECOMBINANT PROTEINS
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Topical term or geographic name entry element SYNTHETIC BIOLOGY
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Topical term or geographic name entry element SYSTEMS BIOLOGY
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Topical term or geographic name entry element YEAST
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Personal name De, S.
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Personal name Mattanovich, D.
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Personal name Ferrer, P.
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Personal name Gasser, B.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1_9ZfawE5cs058wZ9TFmd4p1f733lSLce/view?usp=drivesdk">https://drive.google.com/file/d/1_9ZfawE5cs058wZ9TFmd4p1f733lSLce/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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Source of classification or shelving scheme Clasificación local
Koha item type Documentos solicitados
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-19569 25.06.2025 25.06.2025 Documentos solicitados