Biodegradable, elastomeric coatings with controlled anti-proliferativeagent release for magnesium-based cardiovascular stents (Record no. 53751)

MARC details
000 -LEADER
fixed length control field 02371nam a2200277Ia 4500
003 - CONTROL NUMBER IDENTIFIER
control field MX-MdCICY
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250625162434.0
040 ## - CATALOGING SOURCE
Transcribing agency CICY
090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN)
Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-19628
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
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245 10 - TITLE STATEMENT
Title Biodegradable, elastomeric coatings with controlled anti-proliferativeagent release for magnesium-based cardiovascular stents
490 0# - SERIES STATEMENT
Volume/sequential designation Colloids and Surfaces B: Biointerfaces, 144, p.170-179, 2016
520 3# - SUMMARY, ETC.
Summary, etc. Vascular stent design continues to evolve to further improve the efficacy and minimize the risks associated with these devices. Drug-eluting coatings have been widely adopted and, more recently, biodegradable stents have been the focus of extensive evaluation. In this report, biodegradable elastomeric polyurethanes were synthesized and applied as drug-eluting coatings for a relatively new class of degradable vascular stents based on Mg. The dynamic degradation behavior, hemocompatibility and drug release were investigated for poly(carbonate urethane)urea (PCUU)and poly(ester urethane)urea (PEUU)coated magnesium alloy (AZ31)stents. Poly(lactic-co-glycolic acid)(PLGA)coated and bare stents were employed as control groups. The PCUU coating effectively slowed the Mg alloy corrosion in dynamic degradation testing compared to PEUU-coated, PLGA-coated and bare Mg alloy stents. This was confirmed by electron microscopy, energy-dispersive x-ray spectroscopy and magnesium ion release experiments. PCUU-coating of AZ31 was also associated with significantly reduced platelet adhesion in acute blood contact testing. Rat vascular smooth muscle cell (rSMC)proliferation was successfully inhibited when paclitaxel was released from pre-loaded PCUU coatings. The corrosion retardation, low thrombogenicity, drug loading capacity, and high elasticity make PCUU an attractive option for drug eluting coating on biodegradable metallic cardiovascular stents.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element POLYMER COATING
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element MAGNESIUM STENTS
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element DRUG ELUTING COATING
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Gu, X.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Mao, Z.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Ye, S. H.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Koo, Y.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Yun, Y.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Tiasha, T. R.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Wagner, W. R.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1kmPi0aJLH1c0nYypcCT5X6Y_rvEeo2_a/view?usp=drivesdk">https://drive.google.com/file/d/1kmPi0aJLH1c0nYypcCT5X6Y_rvEeo2_a/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Clasificación local
Koha item type Documentos solicitados
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Lost status Source of classification or shelving scheme Damaged status Not for loan Collection Home library Current library Shelving location Date acquired Total checkouts Full call number Date last seen Price effective from Koha item type
  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-19628 25.06.2025 25.06.2025 Documentos solicitados