An engineered pathway for N-hydroxy-pipecolic acid synthesis enhances systemic acquired resistance in tomato (Record no. 53794)
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| fixed length control field | 01989nam a2200205Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250625162435.0 |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) | |
| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) | B-19671 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT | |
| Title | An engineered pathway for N-hydroxy-pipecolic acid synthesis enhances systemic acquired resistance in tomato |
| 490 0# - SERIES STATEMENT | |
| Volume/sequential designation | Science Signaling, 12(604), p.eaay3066, 2019 |
| 520 3# - SUMMARY, ETC. | |
| Summary, etc. | Systemic acquired resistance (SAR)is a powerful immune response that triggers broad-spectrum disease resistance throughout a plant. In the model plant Arabidopsis thaliana, long-distance signaling and SAR activation in uninfected tissues occur without circulating immune cells and instead rely on the metabolite N-hydroxy-pipecolic acid (NHP). Engineering SAR in crop plants would enable external control of a plant's ability to mount a global defense response upon sudden changes in the environment. Such a metabolite-engineering approach would require the molecular machinery for producing and responding to NHP in the crop plant. Here, we used heterologous expression in Nicotiana benthamiana leaves to identify a minimal set of Arabidopsis genes necessary for the biosynthesis of NHP. Local expression of these genes in tomato leaves triggered SAR in distal tissues in the absence of a pathogen, suggesting that the SAR trait can be engineered to enhance a plant's endogenous ability to respond to pathogens. We also showed tomato produces endogenous NHP in response to a bacterial pathogen and that NHP is present across the plant kingdom, raising the possibility that an engineering strategy to enhance NHP-induced defenses could be possible in many crop plants. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Holmes, E. C. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Chen, Y. C. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Sattely, E. S. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mudgett, M. B. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://drive.google.com/file/d/1_naEq-zWbYhu_tY9b3rX-YuVqt8cf-iB/view?usp=drivesdk">https://drive.google.com/file/d/1_naEq-zWbYhu_tY9b3rX-YuVqt8cf-iB/view?usp=drivesdk</a> |
| Public note | Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Clasificación local |
| Koha item type | Documentos solicitados |
| Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection | Home library | Current library | Shelving location | Date acquired | Total checkouts | Full call number | Date last seen | Price effective from | Koha item type |
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| Clasificación local | Ref1 | CICY | CICY | Documento préstamo interbibliotecario | 25.06.2025 | B-19671 | 25.06.2025 | 25.06.2025 | Documentos solicitados |