Stress responsiveness of vindoline accumulation in Catharanthus roseus leaves is mediated through co.expression of allene oxide cyclase with pathway genes (Record no. 53848)

MARC details
000 -LEADER
fixed length control field 02485nam a2200289Ia 4500
003 - CONTROL NUMBER IDENTIFIER
control field MX-MdCICY
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250625162436.0
040 ## - CATALOGING SOURCE
Transcribing agency CICY
090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN)
Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-19727
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 250602s9999 xx |||||s2 |||| ||und|d
245 10 - TITLE STATEMENT
Title Stress responsiveness of vindoline accumulation in Catharanthus roseus leaves is mediated through co.expression of allene oxide cyclase with pathway genes
490 0# - SERIES STATEMENT
Volume/sequential designation Protoplasma, 259(3), p.755-773, 2022
520 3# - SUMMARY, ETC.
Summary, etc. Vindoline is an important alkaloid produced in Catharanthus roseus leaves. It is the more important monomer of the scarce and costly anticancer bisindole alkaloids, vincristine, and vinblastine, as unlike catharanthine (the other monomer), its biosynthesis is restricted to the leaves. Here, biotic (bacterial endophyte, phytoplasma, virus)and abiotic (temperature, salinity, SA, MeJa)factors were studied for their effect on vindoline accumulation in C. roseus. Variations in vindoline pathway-related gene expression were reflected in changes in vindoline content. Since allene oxide cyclase (CrAOC)is involved in jasmonate biosynthesis and MeJa modulates many vindoline pathway genes, the correlation between CrAOC expression and vindoline content was studied. It was taken up for full-length cloning, tissue-specific expression profiling, in silico analyses, and upstream genomic region analysis for cis-regulatory elements. Co-expression analysis of CrAOC with vindoline metabolism-related genes under the influence of aforementioned abiotic/biotic factors indicated its stronger direct correlation with the tabersonine-to-vindoline genes (t16h, omt, t3o, t3r, nmt, d4h, dat)as compared to the pre-tabersonine genes (tdc, str, sgd). Its expression was inversely related to that of downstream-acting peroxidase (prx)(except under temperature stress). Direct/positive relationship of CrAOC expression with vindoline content established it as a key gene modulating vindoline accumulation in C. roseus.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element ABIOTIC/BIOTIC FACTORS
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element BISINDOLE ALKALOIDS
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element CO-EXPRESSION ANALYSIS
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element JASMONATE
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element VINDOLINE METABOLISM
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Mall, M.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Shanker, K.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Samad, A.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Kalra, A.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Sundaresan, V.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Shukla, A. K.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1DzdTaRhyeSNZOURdkDXpcaoUKws9v_NZ/view?usp=drivesdk">https://drive.google.com/file/d/1DzdTaRhyeSNZOURdkDXpcaoUKws9v_NZ/view?usp=drivesdk</a>
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942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Clasificación local
Koha item type Documentos solicitados
Holdings
Lost status Source of classification or shelving scheme Damaged status Not for loan Collection Home library Current library Shelving location Date acquired Total checkouts Full call number Date last seen Price effective from Koha item type
  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-19727 25.06.2025 25.06.2025 Documentos solicitados