Essential Oil Composition, Antimicrobial and Pharmacological Activities of Lippia sidoides Cham. (Verbenaceae)From São Gonçalo do Abaeté, Minas Gerais, Brazil (Record no. 53992)

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control field MX-MdCICY
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250625162438.0
040 ## - CATALOGING SOURCE
Transcribing agency CICY
090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN)
Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-19883
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245 10 - TITLE STATEMENT
Title Essential Oil Composition, Antimicrobial and Pharmacological Activities of Lippia sidoides Cham. (Verbenaceae)From São Gonçalo do Abaeté, Minas Gerais, Brazil
490 0# - SERIES STATEMENT
Volume/sequential designation Pharmacognosy Magazine, 12(48), p.262, 2016
520 3# - SUMMARY, ETC.
Summary, etc. Lippia sidoides (Verbenaceae)is used in Brazilian folk medicine as an antiseptic, and it is usually applied topically on skin, mucous membranes, mouth, and throat, or used for vaginal washings. Objectives: To analyze the chemical composition of the essential oil from L. sidoides collected in São Gonçalo do Abaeté, Minas Gerais and grown in Hidrolândia, Goiás; to evaluate the antimicrobial activity of the essential oil, crude etanol extract, and hexane, dichloromethane, ethyl-acetate, and aqueous fractions (AFs); to study the antinociceptive, anti-inflammatory, and central nervous system activities of the crude ethanol extract. Materials and methods: The essential oils were obtained by hydro-distillation using a Clevenger-type apparatus and analyzed by GC/MS. The antimicrobial activity in vitro was performed by broth microdilution method. The pharmacological tests were performed using female Swiss albino mice. Results: The major components of the essential oil were isoborneol (14.66 percent), bornyl acetate (11.86 percent), ?-humulene (11.23 percent), ?-fenchene (9.32 percent), and 1.8-cineole (7.05 percent), supporting the existence of two chemotypes of this species. The hexane fraction (HF)had good antifungal activity against Cryptococcus sp. ATCC D (MIC = 31.25 ?g/mL)and Cryptococcus gatti L48 (MIC = 62.5 ?g/mL). In the pharmacological tests, the crude ethanol extract presented antinociceptive and anti-inflammatory activities. Conclusion: Given that the ethanol extract of L. sidoides is included in the Formulary of Phytotherapeutic Agents of the Brazilian Pharmacopeia as an anti-inflammatory for oral cavities, the present work provides scientific evidence to back this use and highlight the importance of selecting the appropriate chemotype on the basis of the expected biological response.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element ANTI-INFLAMMATORY ACTIVITY
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element ANTIMICROBIAL ACTIVITY
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element ANTINOCICEPTIVE ACTIVITY
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element ESSENTIAL OIL
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element LIPPIA SIDOIDES
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name De Morais, S. R.
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Personal name Oliveira, T. L. S.
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Personal name De Oliveira, L. P.
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Personal name Tresvenzol, L. M. F.
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Personal name Da Conceição, E. C.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Rezende, M. H.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name De Paula, J. R.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1YCmVIbsoT546UbOuc8ly2rVOLOjXORdO/view?usp=drivesdk">https://drive.google.com/file/d/1YCmVIbsoT546UbOuc8ly2rVOLOjXORdO/view?usp=drivesdk</a>
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Source of classification or shelving scheme Clasificación local
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-19883 25.06.2025 25.06.2025 Documentos solicitados