MARC details
| 000 -LEADER |
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02493nam a2200265Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20250625162440.0 |
| 040 ## - CATALOGING SOURCE |
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| Transcribing agency |
CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) |
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| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) |
B-19965 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT |
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| Title |
Metabolomics combined to chemometrics reveals the putative á-glucosidase and á-amylase inhibitory metabolites of ground cherry (Physalis pruinosa L.) |
| 490 0# - SERIES STATEMENT |
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| Volume/sequential designation |
Food Research International, 161, p.111903, 2022 |
| 520 3# - SUMMARY, ETC. |
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| Summary, etc. |
In this work, metabolic profiling of the different parts of ground cherry (P. pruinosa)including fruits, calyces, leaves, stems and roots using UPLC-MS/MS analysis combined to chemometric analysis was attempted. A total of 82 chromatographic peaks belonging to different metabolite classes were identified including terpenes, flavonoids genin and glycosides, withanolides, physalins, sucrose esters, fatty acids and other miscellaneous compounds with withanolides being the most predominant class. Roots extracts possessed the highest relative content of the identified 5?,6?-epoxy withanolides and intermediate withanolides, while sucrose esters and flavonoidal glycosides were found in a great abundance in calyces extracts. Moreover, physalins were found in all extracts except for roots extracts. Studying the coefficients plots revealed that terpenes and physalins (physanicantriol, loliolide, physalisitin C)were responsible for discrimination of fruits extracts. Calyces, leaves and stems extracts were found to possess antioxidant activity and higher inhibition of ?-glucosidase activity. In an attempt to identify the compounds responsible for the hypoglycemic activity using both ?-amylase and ?-glucosidase inhibition assays, OPLS models coefficient plots were constructed which indicated that physangulide B, physaperuvin G, neophysalin A, and acylsucroses were positively correlated to ?-glucosidase inhibition, while guaiacyl-primeveroside, phyperunolide C, physalactone, physalolactone C and perulactone, were positively correlated to ?-amylase inhibitory activity. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
GROUND CHERRY |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
PHYSALIS PRUINOSA |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
ANTI-DIABETIC |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
UPLC-MS/MS |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
CHEMOMETRICS |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Mahana, A. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Hammoda, H. M. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Harraz, F. M. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Shawky, E. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
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| Uniform Resource Identifier |
<a href="https://drive.google.com/file/d/1-IVThlIg7fYSpwlmOmGcFjhFbieQJ7Jw/view?usp=drivesdk">https://drive.google.com/file/d/1-IVThlIg7fYSpwlmOmGcFjhFbieQJ7Jw/view?usp=drivesdk</a> |
| Public note |
Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Source of classification or shelving scheme |
Clasificación local |
| Koha item type |
Documentos solicitados |
