GC-MS analysis of phytoconstituents present in methanolic extract of Actinidia deliciosa L. fruits and its antioxidant activity (Record no. 54097)

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control field MX-MdCICY
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250625162440.0
040 ## - CATALOGING SOURCE
Transcribing agency CICY
090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN)
Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-19992
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245 10 - TITLE STATEMENT
Title GC-MS analysis of phytoconstituents present in methanolic extract of Actinidia deliciosa L. fruits and its antioxidant activity
490 0# - SERIES STATEMENT
Volume/sequential designation Journal of the Indian Chemical Society, 10(1), p.16438, 2020
520 3# - SUMMARY, ETC.
Summary, etc. Amomum nilgiricum is one of the plant species reported from Western Ghats of India, belonging to the family Zingiberaceae, with ethno-botanical values, and is well-known for their ethno medicinal applications. In the present investigation, ethyl acetate and methanol extracts of A. nilgiricum were analyzed by Fourier transform infrared spectrometer (FTIR)and gas chromatography-mass spectrometry (GC-MS)to identify the important functional groups and phytochemical constituents. The FTIR spectra revealed the occurrence of functional characteristic peaks of aromatic amines, carboxylic acids, ketones, phenols and alkyl halides group from leaf and rhizome extracts. The GC-MS analysis of ethyl acetate and methanol extracts from leaves, and methanol extract from rhizomes of A. nilgiricum detected the presence of 25 phytochemical compounds. Further, the leaf and rhizome extracts of A. nilgiricum showed remarkable antibacterial and antifungal activities at 100 mg/mL. The results of DPPH and ferric reducing antioxidant power assay recorded maximum antioxidant activity in A. nilgiricum methanolic leaf extract. While, ethyl acetate leaf extract exhibited maximum ?-amylase inhibition activity, followed by methanolic leaf extract exhibiting aldose reductase inhibition. Subsequently, these 25 identified compounds were analyzed for their bioactivity through in silico molecular docking studies. Results revealed that among the phytochemical compounds identified, serverogenin acetate might have maximum antibacterial, antifungal, antiviral, antioxidant and antidiabetic properties followed by 2,4-dimethyl-1,3-dioxane and (1,3-13C2)propanedioic acid. To our best knowledge, this is the first description on the phytochemical constituents of the leaves and rhizomes of A. nilgiricum, which show pharmacological significance, as there has been no literature available yet on GC-MS and phytochemical studies of this plant species. The in silico molecular docking of serverogenin acetate was also performed to confirm its broad spectrum activities based on the binding interactions with the antibacterial, antifungal, antiviral, antioxidant and antidiabetic target proteins. The results of the present study will create a way for the invention of herbal medicines for several ailments by using A. nilgiricum plants, which may lead to the development of novel drugs.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element ACTINIDIA DELICIOSA
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element GC-MS ANALYSIS
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element PHYTOCONSTITUENTS
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element ANTIOXIDANT ACTIVITY
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Qadir, A.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Khan, N.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Ullah, S. N. M. N.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Ali, A.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Gupta, D. K.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Khan, S. A.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1mItXDjzHfFaDSaXX20nhL6UXp6aGtHgA/view?usp=drivesdk">https://drive.google.com/file/d/1mItXDjzHfFaDSaXX20nhL6UXp6aGtHgA/view?usp=drivesdk</a>
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Source of classification or shelving scheme Clasificación local
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-19992 25.06.2025 25.06.2025 Documentos solicitados