HPTLC simultaneous quantification of triterpene acids for quality control of Plantago major L. and evaluation of their cytotoxic and antioxidant activities (Record no. 54255)

MARC details
000 -LEADER
fixed length control field 02287nam a2200265Ia 4500
003 - CONTROL NUMBER IDENTIFIER
control field MX-MdCICY
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250625162443.0
040 ## - CATALOGING SOURCE
Transcribing agency CICY
090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN)
Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-20152
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 250602s9999 xx |||||s2 |||| ||und|d
245 10 - TITLE STATEMENT
Title HPTLC simultaneous quantification of triterpene acids for quality control of Plantago major L. and evaluation of their cytotoxic and antioxidant activities
490 0# - SERIES STATEMENT
Volume/sequential designation Industrial Crops and Products, 60, p.239-246, 2014
520 3# - SUMMARY, ETC.
Summary, etc. A validated high performance thin-layer chromatography (HPTLC)method was developed for simultaneous determination of ursolic acid (UA)and oleanolic acid (OA)contents in Plantago major which were collected from several plantation areas in Indonesia. The cytotoxic effect against two cancer cell lines, SiHa and Hep G2, and antioxidant activity were evaluated using the MTT and DPPH-radical scavenging assay, respectively. The test samples included various extracts of P. major from different plant parts using methanol and water as extracting solvents and pure compounds derived from this plant. The results showed that both plant parts and extracting solvents affected the chemical contents and their biological activities. The contents of UA and OA varied according to the organs and provenances of plant. The highest content of UA (0.22-0.48percent dry weight)and OA (0.17-0.33percent dry weight)were found in the methanol extract of seed. This extract also exhibited the highest cytotoxic activity (IC50 value: 174.42-246.38 ?g/ml), whereas the strongest free radical scavenging activity was obtained from the leaf methanol extract (IC50 value: 263.57 ?g/ml). The developed HPTLC method can be used for routine analysis and standardization of P. major crude drugs, extracts, and/or finished products using UA and OA as appropriate markers for anticancer products.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element CYTOTOXIC
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element ANTIOXIDANT
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element URSOLIC ACID
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element OLEANOLIC ACID
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element HPTLC
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element SIMULTANEOUS ANALYSIS
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Piyaviriyakul, S.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Siripong, P.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Vallisuta, O.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1FRfyHCN-wCbi3BPzcXe9rkVHB-OWHp-X/view?usp=drivesdk">https://drive.google.com/file/d/1FRfyHCN-wCbi3BPzcXe9rkVHB-OWHp-X/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Clasificación local
Koha item type Documentos solicitados
Holdings
Lost status Source of classification or shelving scheme Damaged status Not for loan Collection Home library Current library Shelving location Date acquired Total checkouts Full call number Date last seen Price effective from Koha item type
  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-20152 25.06.2025 25.06.2025 Documentos solicitados