Predicting medicinal resources in Ranunculaceae family by a combined approach using DNA barcodes and chemical metabolites (Record no. 54273)
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| 000 -LEADER | |
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| fixed length control field | 02516nam a2200301Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250625162444.0 |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) | |
| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) | B-20170 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT | |
| Title | Predicting medicinal resources in Ranunculaceae family by a combined approach using DNA barcodes and chemical metabolites |
| 490 0# - SERIES STATEMENT | |
| Volume/sequential designation | PhytoChemistry Letters, 50, p.67-76, 2022 |
| 520 3# - SUMMARY, ETC. | |
| Summary, etc. | Plant taxonomy based on molecular phylogenetic study and/or chemosystematics study has become increasingly important in exploring and utilizing medicinal resources due to the advent of big data era. In this study, we proposed a classifying approach combining DNA and chemical metabolites for the prediction of new medicinal resources. Specifically, we obtained 104 ITS2 barcodes and 847 chemical metabolites from 104 species in Ranunculaceae. Then, phylogenetic tree based on the ITS2 barcode and clustering tree based on structural similarity of metabolites were separately constructed. In addition, we tested the classifying accuracy of the two methods by Baker`s correlation coefficient and the result showed that phylogenetic tree based on the ITS2 barcode was more accurate, giving a higher score of 0.627, whereas clustering tree based on chemical metabolites obtained a lower score of 0.301. Therefore, the natural products of plants might be described using these clades found by ITS2-based methods, and thus new metabolites of plants might be predicted due to the close relationships in a given clade. Using this combined method, 53 plants with structurally similar metabolites were included in 9 plant groups and currently unknown species-metabolite relations were predicted. Finally, 26.92percent species in Ranunculaceae were found to contain the predicted metabolites after verification using two alternative KNApSAcKCore and ChEBI databases. As a whole, the combined approach can successfully classify plants and predict specialized natural products based on plant taxa. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | ITS2 BARCODE |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | MACHINE LEARNING |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | METABOLITES |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | PLANT TAXONOMY |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | RANUNCULACEAE |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | An, Q. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Chen, J. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Tan, G. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ren, Y. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Zhou, J. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Liao, H. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Tan, R. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://drive.google.com/file/d/1dCoJTKet_HQA6yPYtWkFAQReh7253iZS/view?usp=drivesdk">https://drive.google.com/file/d/1dCoJTKet_HQA6yPYtWkFAQReh7253iZS/view?usp=drivesdk</a> |
| Public note | Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Clasificación local |
| Koha item type | Documentos solicitados |
| Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection | Home library | Current library | Shelving location | Date acquired | Total checkouts | Full call number | Date last seen | Price effective from | Koha item type |
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| Clasificación local | Ref1 | CICY | CICY | Documento préstamo interbibliotecario | 25.06.2025 | B-20170 | 25.06.2025 | 25.06.2025 | Documentos solicitados |