Metabolite variation and discrimination of five licorice (Glycyrrhiza)species: HPTLC and NMR explorations (Record no. 54292)

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control field 20250625162444.0
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Transcribing agency CICY
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Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-20189
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Title Metabolite variation and discrimination of five licorice (Glycyrrhiza)species: HPTLC and NMR explorations
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Volume/sequential designation Journal of Pharmaceutical and Biomedical Analysis, 220, p.115012, 2022
520 3# - SUMMARY, ETC.
Summary, etc. The roots and rhizomes of several Glycyrrhiza species are widely used as sweetening and flavoring agents in food, as well as important ingredients in formulations of traditional medicines. Five Glycyrrhiza species, G. uralensis, G. glabra, G. inflata, G. echinata, and G. lepidota, often share the name "licorice roots" in the botanicals' marketplace. Unfortunately, misidentification/mislabeling is very common due to their similarities in morpho-anatomical features. Significant metabolite alterations among the different Glycyrrhiza species and their hybrids have been reported, suggesting that the biological activities could vary with the licorice roots or products derived from different species. Development of simple, effective methods for species identification and differentiation is of key importance. In this study, 78 licorice samples were investigated using HPTLC and NMR as analytical tools. Significant metabolite variations were observed between the five species. The species-specific fingerprint patterns for the five Glycyrrhiza species were determined with HPTLC and NMR; then applied to the sample identification and discrimination. The results obtained from these two orthogonal analytical methods agreed with each other. Furthermore, the NMR signals and the species-specific constituents that made significant contributions to the differentiation of the five Glycyrrhiza species were confirmed based on the multivariate analysis of the NMR spectral data. Using the established OPLS-DA models, the classification of hybrids was evaluated and confirmed. The developed methods, particularly the HPTLC method with its simplicity and low cost, could be used as a rapid and reliable approach for the authentication of licorice species and quality control of licorice raw material and products.
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Personal name Zhao, J.
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Personal name Wang, M.
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Personal name Adams, S. J.
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Personal name Lee, J.
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Personal name Chittiboyina, A. G.
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Personal name Avula, B.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Khan, I. A.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1pNR6rIq4uKiUzjz28dhfPeOb7N49ZAk_/view?usp=drivesdk">https://drive.google.com/file/d/1pNR6rIq4uKiUzjz28dhfPeOb7N49ZAk_/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-20189 25.06.2025 25.06.2025 Documentos solicitados