Chemical synthesis of saponins (Record no. 54294)

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control field MX-MdCICY
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control field 20250625162444.0
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Transcribing agency CICY
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Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-20191
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Title Chemical synthesis of saponins
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Volume/sequential designation Advances in Carbohydrate Chemistry and BioChemistry, 71, p.137-226, 2014
520 3# - SUMMARY, ETC.
Summary, etc. Saponins are a large family of amphiphilic glycosides of steroids and triterpenes found in plants and some marine organisms. By expressing a large diversity of structures on both sugar chains and aglycones, saponins exhibit a wide range of biological and pharmacological properties and serve as major active principles in folk medicines, especially in traditional Chinese medicines. Isolation of saponins from natural sources is usually a formidable task due to the microheterogeneity of saponins in Nature. Chemical synthesis can provide access to large amounts of natural saponins as well as congeners for understanding their structure-activity relationships and mechanisms of action. This article presents a comprehensive account on chemical synthesis of saponins. First highlighted are general considerations on saponin synthesis, including preparation of aglycones and carbohydrate building blocks, assembly strategies, and protecting-group strategies. Next described is the state of the art in the synthesis of each type of saponins, with an emphasis on those representative saponins having sophisticated structures and potent biological activities.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Yang, Y.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Laval, S.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Yu, B.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1BjpD7JrYUP_DMxZbcjfnMNFGUsIoar7K/view?usp=drivesdk">https://drive.google.com/file/d/1BjpD7JrYUP_DMxZbcjfnMNFGUsIoar7K/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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Source of classification or shelving scheme Clasificación local
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-20191 25.06.2025 25.06.2025 Documentos solicitados