Microbiome mediation of animal life histories via metabolites and insulin-like signalling (Record no. 54431)

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fixed length control field 02653nam a2200301Ia 4500
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control field MX-MdCICY
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control field 20250625162447.0
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Transcribing agency CICY
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Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-20335
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Title Microbiome mediation of animal life histories via metabolites and insulin-like signalling
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Volume/sequential designation Biological Reviews, 97(3), p.1118-1130, 2022
520 3# - SUMMARY, ETC.
Summary, etc. The regulatory pathways by which gut microbiota potentially shape host life histories remain largely untested, however, a constellation of research suggests that gut bacteria likely have significant effects on their hosts via metabolites. In this article we review known and hypothesized pathways by which gut microbiota influence host life histories through interfacing with the neuroendocrine system, with a focus on the insulin-like growth factor (IGF)signalling pathway. Bacterially derived metabolites including short-chain fatty acids (SCFAs), polyamines, and peptides likely impact host life histories as metabolic substrates, essential nutrients, and via molecular signalling with well-studied neuroendocrine pathways. The hypothalamus-pituitary axis and insulin-like signalling (ILS)pathways are central regulatory networks for development, growth, reproductive maturity, reproduction, and senescence and are likely targets for tests of how gut bacterial metabolites shape host life histories. SCFAs in particular, as metabolites derived from bacterial fermentation, are implicated as significant microbiome signalling molecules shown to interface with the ILS pathway as well as to bind to receptors on neuroendocrine and peripheral nervous tissues. For example, experimental increases of SCFA production have been shown to affect IGF-1 levels in circulation and are associated with robust development, growth, reproduction, and delayed senescence. Finally, emerging -omics approaches are providing integrative ways to test and detail the potential diverse ways in which gut microbiota interact with their hosts and the likely important roles they play in shaping host life-history responses to varied environmental conditions.
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Topical term or geographic name entry element IGF-1
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Topical term or geographic name entry element DEVELOPMENT
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Topical term or geographic name entry element GROWTH
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Topical term or geographic name entry element MATURITY
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Topical term or geographic name entry element REPRODUCTION
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Topical term or geographic name entry element SENESCENCE
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element GUT BACTERIA
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Topical term or geographic name entry element METABOLITES
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element SHORT-CHAIN FATTY ACIDS
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element POLYAMINES
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Personal name Warne, R. W.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Dallas, J.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1_xPb8zS_hl8-5oY5-1PQcNinUOOeYGGB/view?usp=drivesdk">https://drive.google.com/file/d/1_xPb8zS_hl8-5oY5-1PQcNinUOOeYGGB/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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Source of classification or shelving scheme Clasificación local
Koha item type Documentos solicitados
Holdings
Lost status Source of classification or shelving scheme Damaged status Not for loan Collection Home library Current library Shelving location Date acquired Total checkouts Full call number Date last seen Price effective from Koha item type
  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-20335 25.06.2025 25.06.2025 Documentos solicitados