Natural biopolymers derived hydrogels with injectable, self-healing, and tissue adhesive abilities for wound healing (Record no. 54440)
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| fixed length control field | 02412nam a2200301Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250625162447.0 |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) | |
| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) | B-20344 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT | |
| Title | Natural biopolymers derived hydrogels with injectable, self-healing, and tissue adhesive abilities for wound healing |
| 490 0# - SERIES STATEMENT | |
| Volume/sequential designation | Nano Research, 16(2), p.2798-2807, 2023 |
| 520 3# - SUMMARY, ETC. | |
| Summary, etc. | Developing a biocompatible and multifunctional adhesive hydrogel with injectability and self-healing ability for promoting wound healing is highly anticipated in various clinical applications. In this paper, we present a novel natural biopolymer-derived hydrogel based on the aldehyde-modified oxidized guar gum (OGG)and the carboxymethyl chitosan (CMCS)for efficiently improving wound healing with the encapsulation of vascular endothelial growth factor (VEGF). As the hydrogels are synthesized via the dynamically reversible Schiff base linkages, it is imparted with excellent self-healing ability and good shear thinning behavior, which make the hydrogel be easily and conveniently injected through a needle. Besides, the physiochemical properties, including porous structure, mechanical strength and swelling ratio of the hydrogel can be well controlled by regulating the concentrations of the OGG. Moreover, the hydrogel can attain strong adhesion to the tissues at physiological temperature based on the Schiff base between the aldehyde group on the hydrogel and the amino group on the tissue. Based on these features, we have demonstrated that the VEGF encapsulated hydrogel can adhere tightly to the defect tissue and improve wound repair in the rat model of defected skin by promoting cell proliferation, angiogenesis, and collagen secretion. These results indicate that the multifunctional hydrogel is with great scientific significance and broad clinical application prospects. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | HYDROGEL |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | SELF-HEALING |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | INJECTABILITY |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | TISSUE ADHESIVE |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | WOUND HEALING |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kong, B. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Liu, R. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Cheng, Y. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Cai, X. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Liu, J. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Zhang, D. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Zhao, Y. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://drive.google.com/file/d/1lNDUMP3PPxIpPN_d0HSQg9NObzEAfYCT/view?usp=drivesdk">https://drive.google.com/file/d/1lNDUMP3PPxIpPN_d0HSQg9NObzEAfYCT/view?usp=drivesdk</a> |
| Public note | Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Clasificación local |
| Koha item type | Documentos solicitados |
| Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection | Home library | Current library | Shelving location | Date acquired | Total checkouts | Full call number | Date last seen | Price effective from | Koha item type |
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| Clasificación local | Ref1 | CICY | CICY | Documento préstamo interbibliotecario | 25.06.2025 | B-20344 | 25.06.2025 | 25.06.2025 | Documentos solicitados |