Cytokinin modulates the metabolic network of sulfur and glutathione (Record no. 54563)

MARC details
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fixed length control field 02562nam a2200325Ia 4500
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control field MX-MdCICY
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control field 20250625162449.0
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Transcribing agency CICY
090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN)
Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-20472
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Title Cytokinin modulates the metabolic network of sulfur and glutathione
490 0# - SERIES STATEMENT
Volume/sequential designation Journal of Experimental Botany, 73(22), p.7417-7433, 2022
520 3# - SUMMARY, ETC.
Summary, etc. The phytohormone cytokinin is implicated in a range of growth, developmental, and defense processes. A growing body of evidence supports a crosstalk between cytokinin and nutrient signaling pathways, such as nitrate availability. Cytokinin signaling regulates sulfur-responsive gene expression, but the underlying molecular mechanisms and their impact on sulfur-containing metabolites have not been systematically explored. Using a combination of genetic and pharmacological tools, we investigated the interplay between cytokinin signaling and sulfur homeostasis. Exogenous cytokinin triggered sulfur starvation-like gene expression accompanied by a decrease in sulfate and glutathione content. This process was uncoupled from the activity of the major transcriptional regulator of sulfate starvation signaling SULFUR LIMITATION 1 and an important glutathione-degrading enzyme, ?-glutamyl cyclotransferase 2;1, expression of which was robustly up-regulated by cytokinin. Conversely, glutathione accumulation was observed in mutants lacking the cytokinin receptor ARABIDOPSIS HISTIDINE KINASE 3 and in cytokinin-deficient plants. Cytokinin-deficient plants displayed improved root growth upon exposure to glutathione-depleting chemicals which was attributed to a higher capacity to maintain glutathione levels. These results shed new light on the interplay between cytokinin signaling and sulfur homeostasis. They position cytokinin as an important modulator of sulfur uptake, assimilation, and remobilization in plant defense against xenobiotics and root growth.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element ARABIDOPSIS THALIANA
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element CYTOKININ
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element GLUTATHIONE
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element NUTRIENT HOMEOSTASIS
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element SULFUR METABOLISM
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element SULFUR STARVATION
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element XENOBIOTIC TOLERANCE
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Pavlu, J.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Kerchev, P.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Cerný, M.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Novák, J.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Berka, M.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Jobe, T. O.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Brzobohatý, B.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1vFKn_znBQj4z8Xu-PYW9fuRdvGcD1568/view?usp=drivesdk">https://drive.google.com/file/d/1vFKn_znBQj4z8Xu-PYW9fuRdvGcD1568/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Clasificación local
Koha item type Documentos solicitados
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Lost status Source of classification or shelving scheme Damaged status Not for loan Collection Home library Current library Shelving location Date acquired Total checkouts Full call number Date last seen Price effective from Koha item type
  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-20472 25.06.2025 25.06.2025 Documentos solicitados