Is specialized metabolite regulation specialized? (Record no. 54590)

MARC details
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fixed length control field 02169nam a2200241Ia 4500
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control field MX-MdCICY
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control field 20250625162450.0
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Transcribing agency CICY
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Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-20499
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Title Is specialized metabolite regulation specialized?
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Volume/sequential designation Journal of Experimental Botany, 74(17), p.4942-4948, 2023
520 3# - SUMMARY, ETC.
Summary, etc. Recent technical and theoretical advances have generated an explosion in the identification of specialized metabolite pathways. In comparison, our understanding of how these pathways are regulated is relatively lagging. This and the relatively young age of specialized metabolite pathways has partly contributed to a default and common paradigm whereby specialized metabolite regulation is theorized as relatively simple with a few key transcription factors and the compounds are non-regulatory end-products. In contrast, studies into model specialized metabolites, such as glucosinolates, are beginning to identify a new understanding whereby specialized metabolites are highly integrated into the plants' core metabolic, physiological, and developmental pathways. This model includes a greatly extended compendium of transcription factors controlling the pathway, key transcription factors that co-evolve with the pathway and simultaneously control core metabolic and developmental components, and finally the compounds themselves evolve regulatory connections to integrate into the plants signaling machinery. In this review, these concepts are illustrated using studies in the glucosinolate pathway within the Brassicales. This suggests that the broader community needs to reconsider how they do or do not integrate specialized metabolism into the regulatory network of their study species.
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Topical term or geographic name entry element DEVELOPMENT
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Topical term or geographic name entry element GLUCOSINOLATE
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Topical term or geographic name entry element REGULATION
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Topical term or geographic name entry element SPECIALIZED METABOLITE
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Topical term or geographic name entry element STRESS
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element TRANSCRIPTION FACTOR
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Kliebenstein, D. J.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1-T9GxallH_gkfHAYrDj2PqqLqKF6KBUv/view?usp=drivesdk">https://drive.google.com/file/d/1-T9GxallH_gkfHAYrDj2PqqLqKF6KBUv/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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Source of classification or shelving scheme Clasificación local
Koha item type Documentos solicitados
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-20499 25.06.2025 25.06.2025 Documentos solicitados