MARC details
| 000 -LEADER |
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| fixed length control field |
02583nam a2200301Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20250625162452.0 |
| 040 ## - CATALOGING SOURCE |
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| Transcribing agency |
CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) |
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| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) |
B-20614 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT |
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| Title |
Extraction technology, components analysis and anti-inflammatory activity in vitro of total flavonoids extract from Artemisia anomala S. Moore |
| 490 0# - SERIES STATEMENT |
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| Volume/sequential designation |
Fitoterapia, 170, p.105630, 2023 |
| 520 3# - SUMMARY, ETC. |
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| Summary, etc. |
Artemisia anomala S. Moore exerts many pharmacological activities, including the removing of the blood stasis, relieving of the fever and analgesia, reducing the swelling and dampness. In this study, the extraction technology, chemical compositions and anti-inflammatory effect in vitro and mechanism of total flavonoids extract from Artemisia anomala S. Moore were studied. The optimal yield rate of total flavonoids extract was optimized by single factor experiments and response surface method, and the chemical constituents were analyzed by UPLC-QTOF-MS method; and the anti-inflammatory activity of the extract was evaluated with lipopolysaccharide induced RAW 264.7 cells. The highest extraction rate was 2.02 percent under these conditions of the concentration of ethanol 50 percent, the ultrasonic extraction time 30 min, and the ratio of solvent volume to material weight 20:1 (ml/g). In addition, the main components of total flavonoid extract were preliminarily identified and deduced based on mass spectrometry information and relevant literatures, and its stronger anti-inflammatory activity was demonstrated by reducing the phagocytosis, the content of nitric oxide and the level of related cytokines (tumor necrosis factor-?, interleukin-10, interleukin-6). Furthermore, it was further revealed that the anti-inflammatory effect of the extract was closely connected with the activation of TLR4-MyD88-NF-?B signalling pathway. This study indicated that the total flavonoids extract from Artemisia anomala S. Moore may be a better candidate anti-inflammatory natural medicine. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
ANTI-INFLAMMATION |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
ARTEMISIA ANOMALA S. MOORE |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
COMPONENTS ANALYSIS |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
TLR4-MYD88-NF-?B SIGNALLING PATHWAY |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
TOTAL FLAVONOIDS |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Shao, Y. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Hong, R. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Li, B. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Wang, A. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Chen, Y. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Wang, Y. |
| 700 12 - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Tian, C. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
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| Uniform Resource Identifier |
<a href="https://drive.google.com/file/d/1vztIHemkTy1MlED974uZQ-Ti6bnGjF_4/view?usp=drivesdk">https://drive.google.com/file/d/1vztIHemkTy1MlED974uZQ-Ti6bnGjF_4/view?usp=drivesdk</a> |
| Public note |
Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Source of classification or shelving scheme |
Clasificación local |
| Koha item type |
Documentos solicitados |
