NLR functions in plant and animal immune systems: so far and yet so close (Record no. 54713)

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control field MX-MdCICY
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control field 20250625162452.0
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Transcribing agency CICY
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Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-20627
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Title NLR functions in plant and animal immune systems: so far and yet so close
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Volume/sequential designation Nature immunology, 12(9), p.817-826, 2011
520 3# - SUMMARY, ETC.
Summary, etc. In plants and animals, the NLR family of receptors perceives non-self and modified-self molecules inside host cells and mediates innate immune responses to microbial pathogens. Despite their similar biological functions and protein architecture, animal NLRs are normally activated by conserved microbe- or damage-associated molecular patterns, whereas plant NLRs typically detect strain-specific pathogen effectors. Plant NLRs recognize either the effector structure or effector-mediated modifications of host proteins. The latter indirect mechanism for the perception of non-self, as well as the within-species diversification of plant NLRs, maximize the capacity to recognize non-self through the use of a finite number of innate immunoreceptors. We discuss recent insights into NLR activation, signal initiation through the homotypic association of N-terminal domains and subcellular receptor dynamics in plants and compare those with NLR functions in animals.
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Personal name Maekawa, T.
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Personal name Kufer, T. A.
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Personal name Schulze-Lefert, P.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1ZDDHX97aO7QjA_L4Z54wSReMraFYX5cf/view?usp=drivesdk">https://drive.google.com/file/d/1ZDDHX97aO7QjA_L4Z54wSReMraFYX5cf/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-20627 25.06.2025 25.06.2025 Documentos solicitados