Chemical profile, antiproliferative and antibacterial activities and docking studies of essential oil and hexane fraction of hydrosol from fresh leaf of Plectranthus amboinicus (Lour.)Spreng. (Record no. 54729)
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| fixed length control field | 02568nam a2200289Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250625162452.0 |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) | |
| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) | B-20643 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT | |
| Title | Chemical profile, antiproliferative and antibacterial activities and docking studies of essential oil and hexane fraction of hydrosol from fresh leaf of Plectranthus amboinicus (Lour.)Spreng. |
| 490 0# - SERIES STATEMENT | |
| Volume/sequential designation | BioChemical Systematics and Ecology, 107, p.104595, 2023 |
| 520 3# - SUMMARY, ETC. | |
| Summary, etc. | Essential oils are commonly extracted from plants by hydrodistillation in which an aqueous phase called hydrosol is obtained. Like essential oil, this by-product of distillation can be a source of natural bioactive molecules with health benefits. This study aimed at the investigation of the chemical profile, antiproliferative and antibacterial activities of essential oil and hexane fraction of hydrosol from Plectrunthus amboinicus (family Lamiacease)fresh leaf cultivated in Sudan. Essential oil was obtained by hydrodistilation and hexane fraction (HF)was derived from hydrosol by liquid -liquid extraction. Results showed that the phenolic monoterpene thymol (72.9 percent)was the dominant component of the essential oil while the HF was characterized by the presence of long-chain (n-C29 to n-C68)alkanes (91.4 percent). The HF showed highest antiproliferative activity against the colon cancer HT29 (IC50 9.2 ?g/mL)and HCT116 (IC50 7.7 ?g/mL)cell lines. The essential oil exerted best antibacterial activity with highest inhibition (22.0-22.3 mm)and minimum inhibitory concentration (31 ?g/mL)against the Gram positive bacteria Bacillus subtilis and Staphylococcus aureus. In silico study showed that the major components of the oil displayed higher docking scores than those present in the HF suggesting an antagonistic effect by other molecules in the essential oil. In conclusion, beside the essential oil, the hydrosol possesses promising bioactive composition suggesting that it could be exploited for further therapeutic applications. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | PLECTRANTHUS AMBOINICUS |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | ESSENTIAL OIL |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | HYDROSOL |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | ANTIPROLIFERATIVE |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | ANTIBACTERIAL |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ibrahim, E. I. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Yagi, S. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Tzanova, T. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Schohn, H. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Uba, A. I. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Zengin, G. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://drive.google.com/file/d/1gYVwPY8L4EQAy3Zxd3x0CJQDu7c-IVL-/view?usp=drivesdk">https://drive.google.com/file/d/1gYVwPY8L4EQAy3Zxd3x0CJQDu7c-IVL-/view?usp=drivesdk</a> |
| Public note | Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Clasificación local |
| Koha item type | Documentos solicitados |
| Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection | Home library | Current library | Shelving location | Date acquired | Total checkouts | Full call number | Date last seen | Price effective from | Koha item type |
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| Clasificación local | Ref1 | CICY | CICY | Documento préstamo interbibliotecario | 25.06.2025 | B-20643 | 25.06.2025 | 25.06.2025 | Documentos solicitados |