Manual correction of genome annotation improved alternative splicing identification of Artemisia annua (Record no. 54755)

MARC details
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fixed length control field 02194nam a2200301Ia 4500
003 - CONTROL NUMBER IDENTIFIER
control field MX-MdCICY
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250625162453.0
040 ## - CATALOGING SOURCE
Transcribing agency CICY
090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN)
Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-20669
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245 10 - TITLE STATEMENT
Title Manual correction of genome annotation improved alternative splicing identification of Artemisia annua
490 0# - SERIES STATEMENT
Volume/sequential designation Planta, 258(4), p.83, 2023
520 3# - SUMMARY, ETC.
Summary, etc. Gene annotation is essential for genome-based studies. However, algorithm-based genome annotation is difficult to fully and correctly reveal genomic information, especially for species with complex genomes. Artemisia annua L. is the only commercial resource of artemisinin production though the content of artemisinin is still to be improved. Genome-based genetic modification and breeding are useful strategies to boost artemisinin content and therefore, ensure the supply of artemisinin and reduce costs, but better gene annotation is urgently needed. In this study, we manually corrected the newly released genome annotation of A. annua using second- and third-generation transcriptome data. We found that incorrect gene information may lead to differences in structural, functional, and expression levels compared to the original expectations. We also identified alternative splicing events and found that genome annotation information impacted identifying alternative splicing genes. We further demonstrated that genome annotation information and alternative splicing could affect gene expression estimation and gene function prediction. Finally, we provided a valuable version of A. annua genome annotation and demonstrated the importance of gene annotation in future research.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element ALTERNATIVE SPLICING
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element ARTEMISIA ANNUA
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element ARTEMISININ
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element GENOME ANNOTATION
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element MANUAL CORRECTION
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Liu, Z.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Du, Y.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Sun, Z.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Cheng, B.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Bi, Z.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Yao, Z.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Chen, S.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1k9z9bbms4jp6xE1pA6R9Ghe96oRjflOG/view?usp=drivesdk">https://drive.google.com/file/d/1k9z9bbms4jp6xE1pA6R9Ghe96oRjflOG/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Clasificación local
Koha item type Documentos solicitados
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-20669 25.06.2025 25.06.2025 Documentos solicitados