Co-delivery of hydrophobic astaxanthin and hydrophilic phycocyanin by a pH-sensitive water-in-oil-in-water double emulsion-filled gellan gum hydrogel (Record no. 54851)

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fixed length control field 02815nam a2200313Ia 4500
003 - CONTROL NUMBER IDENTIFIER
control field MX-MdCICY
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250625162455.0
040 ## - CATALOGING SOURCE
Transcribing agency CICY
090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN)
Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-20770
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
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245 10 - TITLE STATEMENT
Title Co-delivery of hydrophobic astaxanthin and hydrophilic phycocyanin by a pH-sensitive water-in-oil-in-water double emulsion-filled gellan gum hydrogel
490 0# - SERIES STATEMENT
Volume/sequential designation Food Hydrocolloids, 131, p.107810, 2022
520 3# - SUMMARY, ETC.
Summary, etc. Astaxanthin and phycocyanin were recommended for their bioactivities. However, limited stability and low bioavailability were not conducive to their applications in the food industry. A pH-sensitive double W1/O/W2 emulsion-filled hydrogel loaded concomitantly with astaxanthin and phycocyanin was prepared using the two-step emulsification process. First, the W1/O emulsion was fabricated using polyglycerol polyricinoleate as a hydrophobic emulsifier. Second, W1/O/W2 emulsions are typically formed by homogenizing W1/O emulsions with an aqueous phase containing sodium caseinate. Later, gellan gum was added to the double emulsion as an additional stabilizer and gelling agent to prepare the double emulsion-filled hydrogel. The influence of gellan gum on the microstructure, rheology, and stability of double emulsions was investigated. The double emulsions remained stable during 30 days' storage when the content of gellan gum was above 0.4 percent since the hydrogel formation. The microstructure of double emulsions was maintained under the acidic environment due to the network formed by gellan gum while transformed from hydrogel state to solution state since the disintegration of gellan gum network under neutral conditions. Further, based on the pH-sensitive nature of double emulsion-filled hydrogel, the co-encapsulation of phycocyanin and astaxanthin and the in vitro release behavior were demonstrated. The maximum encapsulation efficiency of phycocyanin and astaxanthin was 94.1 percent and 90.82 percent, respectively. In vitro digestion proved their intestinal targeted release ability. These results suggested that the double emulsion-filled gellan gum hydrogel can be used as a pH-sensitive carrier for intestinal targeted delivery of hydrophobic and hydrophilic food bioactive ingredients.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element PH-SENSITIVE
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element CONTROLLED-RELEASE
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element WATER-IN-OIL-IN-WATER
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element GELLAN GUM
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element ASTAXANTHIN
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element PHYCOCYANIN
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Yu, H.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Wang, H.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Su, W.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Song, Y.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Zaky, A. A.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Abd El-Aty, A. M.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Tan, M.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1eSnPsVi4zCE0HTRQckf1hV6G4f5tpFdz/view?usp=drivesdk">https://drive.google.com/file/d/1eSnPsVi4zCE0HTRQckf1hV6G4f5tpFdz/view?usp=drivesdk</a>
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Source of classification or shelving scheme Clasificación local
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Lost status Source of classification or shelving scheme Damaged status Not for loan Collection Home library Current library Shelving location Date acquired Total checkouts Full call number Date last seen Price effective from Koha item type
  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-20770 25.06.2025 25.06.2025 Documentos solicitados