Zika virus: Antiviral immune response, inflammation, and cardiotonic steroids as antiviral agents (Record no. 54960)

MARC details
000 -LEADER
fixed length control field 02045nam a2200289Ia 4500
003 - CONTROL NUMBER IDENTIFIER
control field MX-MdCICY
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250625162457.0
040 ## - CATALOGING SOURCE
Transcribing agency CICY
090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN)
Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-20880
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 250602s9999 xx |||||s2 |||| ||und|d
245 10 - TITLE STATEMENT
Title Zika virus: Antiviral immune response, inflammation, and cardiotonic steroids as antiviral agents
490 0# - SERIES STATEMENT
Volume/sequential designation International ImmunoPharmacology, 127, p.111368, 2024
520 3# - SUMMARY, ETC.
Summary, etc. Zika virus (ZIKV)is a mosquito-borne virus first reported from humans in Nigeria in 1954. The first outbreak occurred in Micronesia followed by an outbreak in French Polynesia and another in Brazil when the virus was associated with numerous cases of severe neurological manifestations such as Guillain-Barre syndrome in adults and congenital zika syndrome in fetuses, particularly congenital microcephaly. Innate immunity is the first line of defense against ZIKV through triggering an antiviral immune response. Along with innate immune responses, a sufficient balance between anti- and pro-inflammatory cytokines and the amount of these cytokines are triggered to enhance the antiviral responses. Here, we reviewed the complex interplay between the mediators and signal pathways that coordinate antiviral immune response and inflammation as a key to understanding the development of the underlying diseases triggered by ZIKV. In addition, we summarize current and new therapeutic strategies for ZIKV infection, highlighting cardiotonic steroids as antiviral drugs for the development of this agent.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element ARBOVIRUS
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element CYTOKINES
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element IMMUNE RESPONSE
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element OUABAIN
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element ZIKV
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name De Sales-Neto, J. M.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Carvalho, D. C. M.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Magalhães, D. W. A.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Medeiros, A. B. A.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Soares, M. M.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Rodrigues-Mascarenhas, S.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1DSSVv50bjduvfFh-Rd7NmcyZDUSlRhiC/view?usp=drivesdk">https://drive.google.com/file/d/1DSSVv50bjduvfFh-Rd7NmcyZDUSlRhiC/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Clasificación local
Koha item type Documentos solicitados
Holdings
Lost status Source of classification or shelving scheme Damaged status Not for loan Collection Home library Current library Shelving location Date acquired Total checkouts Full call number Date last seen Price effective from Koha item type
  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-20880 25.06.2025 25.06.2025 Documentos solicitados