Guide to collagen characterization for biomaterial studies (Record no. 55116)

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003 - CONTROL NUMBER IDENTIFIER
control field MX-MdCICY
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250625162500.0
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Transcribing agency CICY
090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN)
Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-21038
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
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245 10 - TITLE STATEMENT
Title Guide to collagen characterization for biomaterial studies
490 0# - SERIES STATEMENT
Volume/sequential designation Journal of Biomedical Materials Research Part B: Applied BioMaterials, 87(1), p.264-285, 2008
520 3# - SUMMARY, ETC.
Summary, etc. The structure and remodeling of collagen in vivo is critical to the pathology and healing of many human diseases, as well as to normal tissue development and regeneration. In addition, collagen matrices in the form of fibers, coatings, and films are used extensively in biomaterial and biomedical applications. The specific properties of these matrices, both in terms of physical and chemical characteristics, have a direct impact on cellular adhesion, spreading, and proliferation rates, and ultimately on the rate and extent of new extracellular matrix formation in vitro or in vivo. In recent studies, it has also been shown that collagen matrix structure has a major impact on cell and tissue outcomes related to cellular aging and differentiation potential. Collagen structure is complex because of both diversity of source materials, chemistry, and structural hierarchy. With such significant impact of collagen features on biological outcomes, it becomes essential to consider an appropriate set of analytical tools, or guide, so that collagens attained from commercial vendors are characterized in a comparative manner as an integral part of studies focused on biological parameters. The analysis should include as a starting point: (a)structural detail-mainly focused on molecular mass, purity, helical content, and bulk thermal properties, (b)chemical features-mainly focused on surface elemental analysis and hydrophobicity, and (c)morphological features at different length scales. The application of these analytical techniques to the characterization of collagen biomaterial matrices is critical in order to appropriately correlate biological responses from different studies with experimental outcomes in vitro or in vivo. As a case study, the analytical tools employed for collagen biomaterial studies are reviewed in the context of collagen remodeling by fibroblasts. The goal is to highlight the necessity of understanding collagen biophysical and chemical features as a prerequisite to (a)studies with cells and tissue formation, and (b)suggest modes to establish comparative outcomes for studies conducted in different laboratories.
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element COLLAGEN
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element CHARACTERIZATION
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element DENATURED; STRUCTURE
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element BIOMATERIALS
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Abraham, L. C.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Zuena, E.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Perez-Ramirez, B.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Kaplan, D. L.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/open?id=1EsCOTVoGhruKiS875opqs0EMzy8xO8BR&usp=drive_copy">https://drive.google.com/open?id=1EsCOTVoGhruKiS875opqs0EMzy8xO8BR&usp=drive_copy</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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Source of classification or shelving scheme Clasificación local
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-21038 25.06.2025 25.06.2025 Documentos solicitados