Hierarchically structured phycocyanin-loaded micro/nanofibrous membrane for guided bone regeneration (Record no. 55257)
[ view plain ]
| 000 -LEADER | |
|---|---|
| fixed length control field | 02801nam a2200289Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250625164350.0 |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) | |
| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) | B-21180 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT | |
| Title | Hierarchically structured phycocyanin-loaded micro/nanofibrous membrane for guided bone regeneration |
| 490 0# - SERIES STATEMENT | |
| Series statement | Materials Today Communications. 36, 106852, 2023, 10.1016/j.mtcomm.2023.106852 |
| 520 3# - SUMMARY, ETC. | |
| Summary, etc. | Although bone tissues possess an excellent inherent repair capacity, the ability to repair bone defects associated with osteoporosis, osteosarcoma, and congenital anomalies remains challenging. Several previous studies have developed biomaterials such as hydrogels, three-dimensional (3D) scaffolds, and nanofibrous scaffolds using synthetic and natural biomaterials that can deliver bioactive natural products to accelerate bone repair. Here, we evaluated the cytotoxicity, alkaline phosphatase activity, and mineral deposition capacity of MC3T3-E1 cells treated with Spirulina maxima-derived phycocyanin (PC), as well as the effects of PC on the expression of osteogenic protein markers such as osteocalcin and osteopontin in MC3T3-E1 cells. Next, we fabricated a PC-loaded poly lactic acid (PLA) and sodium alginate (SA) micro/nanofibrous membrane using emulsion electrospinning technology and generated hierarchically structured membranes using atelocollagen (AC) isolated from Paralichthys olivaceus. The microstructural architecture and physicochemical properties of the fabricated fibrous membranes were evaluated via scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR), X-ray diffraction spectroscopy (XRD), and water contact angle analyses. The fabricated hierarchically structured micro/nanofibrous membrane exhibited excellent in vitro biocompatibility, cytoskeleton organization, and mineral deposition. The fibrous membranes implanted into calvarial bone defect models were evaluated 12 weeks after surgery using micro-CT and histological analysis and the results confirmed that the implant could significantly enhance bone tissue regeneration. Overall, our findings confirmed that PC loaded hierarchically arranged micro/nanofibrous membranes have significant potential for bone tissue regeneration applications. © 2023 |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | ATELOCOLLAGEN |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | BONE REGENERATION |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | FIBROUS MEMBRANE |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | PHYCOCYANIN |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kim S.-C. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Heo S.-Y. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Oh G.-W. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Chandika P. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Park W.S. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Choi I.-W. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Jung W.-K. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://drive.google.com/file/d/1xHIkVNhgq3ZCG1I0qIfKb3R_Fj8UYszO/view?usp=drivesdk">https://drive.google.com/file/d/1xHIkVNhgq3ZCG1I0qIfKb3R_Fj8UYszO/view?usp=drivesdk</a> |
| Public note | Para ver el documento ingresa a Google con tu cuenta @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Clasificación local |
| Koha item type | Documentos solicitados |
| Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection | Home library | Current library | Shelving location | Date acquired | Total checkouts | Full call number | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Clasificación local | Ref1 | CICY | CICY | Documento préstamo interbibliotecario | 25.06.2025 | B-21180 | 25.06.2025 | 25.06.2025 | Documentos solicitados |