Delivery of siRNA therapeutics using cowpea chlorotic mottle virus-like particles (Record no. 55306)

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control field MX-MdCICY
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control field 20250625164351.0
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Transcribing agency CICY
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Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-21236
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Title Delivery of siRNA therapeutics using cowpea chlorotic mottle virus-like particles
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Series statement Biomaterials Science. 7(8), 3138-3142, 2019, DOI: 10.1039/c9bm00785g
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Summary, etc. While highly promising in medicine, gene therapy requires delivery agents to protect and target nucleic acid therapeutics. We developed a plant viral siRNA delivery platform making use of self-assembling cowpea chlorotic mottle virus (CCMV). CCMV was loaded with siRNAs targeting GFP or FOXA1; to further enhance cell uptake and intracellular trafficking, resulting in more efficient gene knockdown, we appended CCMV with a cell penetrating peptide (CPP), specifically M-lycotoxin peptide L17E. © 2019 The Royal Society of Chemistry.
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Personal name Lam P.
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Personal name Steinmetz N.F.
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Uniform Resource Identifier <a href="https://drive.google.com/file/d/1JnRlUyw5qQ21MxFH7Bx4guXgG04Jhj3S/view?usp=drivesdk">https://drive.google.com/file/d/1JnRlUyw5qQ21MxFH7Bx4guXgG04Jhj3S/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta @cicy.edu.mx
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-21236 25.06.2025 25.06.2025 Documentos solicitados