Preparation and structural characterization of surface modified microporous bacterial cellulose scaffolds: A potential material for skin regeneration applications in vitro and in vivo (Record no. 55350)
[ view plain ]
| 000 -LEADER | |
|---|---|
| fixed length control field | 02540nam a2200337Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250625164352.0 |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) | |
| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) | B-21282 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT | |
| Title | Preparation and structural characterization of surface modified microporous bacterial cellulose scaffolds: A potential material for skin regeneration applications in vitro and in vivo |
| 490 0# - SERIES STATEMENT | |
| Series statement | International Journal of Biological Macromolecules. 117, 1200-1210, 2018, DOI: 10.1016/j.ijbiomac.2018.06.044 |
| 520 3# - SUMMARY, ETC. | |
| Summary, etc. | This study reports the fabrication of porogen-induced, surface-modified, 3-dimensionally microporous regenerated bacterial cellulose (rBC)/gelatin (3DMP rBC/G) scaffolds for skin regeneration applications. Round shaped gelatin microspheres (GMS), fabricated using a water-in-oil emulsion (WOE) method, were utilized as the porogen. The dissolution of GMS from the solution casted BC scaffolds led to surface-modified microporous rBC. The scaffolds were characterized using field emission scanning electron microscopy (FE-SEM) and elemental analysis. FE-SEM analysis confirmed the regular microporosity of the 3DMP rBC/G scaffolds, while elemental analysis confirmed the successful surface modification of cellulose with gelatin. In vitro tests showed good adhesion and proliferation of human keratinocytes (HaCaT) on the 3DMP rBC/G scaffolds during 7 days of incubation. Confocal microscopy showed penetration of HaCaT cells into the scaffolds, up to 300 ?m in depth. In vivo wound healing and skin regeneration experiments, in experimental mice, showed complete skin regeneration within 2 weeks. The wound closure efficacy of the 3DMP rBC/G scaffolds was much higher (93%) than that of the control (47%) and pure BC-treated (63%) wounds. These results indicated that our 3DMP rBC/G scaffolds represent future candidate materials for skin regeneration applications. © 2017 Elsevier B.V. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | BACTERIAL CELLULOSE |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | BIOCOMPATIBILITY |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | MICROSPHERES |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | POROGEN |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | SCAFFOLD |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | SKIN REGENERATION |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Khan S. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ul-Islam M. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ikram M. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Islam S.U. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ullah M.W. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Israr M. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Jang J.H. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Yoon S. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Park J.K. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://drive.google.com/file/d/1203ggOxTAgLt1LK_9pJQ3Wa6z1Ws9k-9/view?usp=drivesdk">https://drive.google.com/file/d/1203ggOxTAgLt1LK_9pJQ3Wa6z1Ws9k-9/view?usp=drivesdk</a> |
| Public note | Para ver el documento ingresa a Google con tu cuenta @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Clasificación local |
| Koha item type | Documentos solicitados |
| Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection | Home library | Current library | Shelving location | Date acquired | Total checkouts | Full call number | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Clasificación local | Ref1 | CICY | CICY | Documento préstamo interbibliotecario | 25.06.2025 | B-21282 | 25.06.2025 | 25.06.2025 | Documentos solicitados |