Preparation of sodium fluoride-loaded gelatin microspheres, characterization and cariostatic studies (Record no. 55351)
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| 000 -LEADER | |
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| fixed length control field | 02357nam a2200301Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | MX-MdCICY |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250625164352.0 |
| 040 ## - CATALOGING SOURCE | |
| Transcribing agency | CICY |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) | |
| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) | B-21283 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250602s9999 xx |||||s2 |||| ||und|d |
| 245 10 - TITLE STATEMENT | |
| Title | Preparation of sodium fluoride-loaded gelatin microspheres, characterization and cariostatic studies |
| 490 0# - SERIES STATEMENT | |
| Series statement | Journal of Microencapsulation. 21(8), 889-903, 2004, DOI: 10.1080/02652040400015445 |
| 520 3# - SUMMARY, ETC. | |
| Summary, etc. | Sodium fluoride-loaded gelatin microspheres (NaF-GMS) were prepared using double-phase emulsified condensation polymerization. The average diameter of microspheres was (11.33±5.56) ?m. The drug content and encapsulation efficiency were 8.80% and 76.73%, respectively. The fluoride releasing profiles of NaF-GMS in physiological saline and artificial saliva (pH 4.5, pH 6.8) showed that NaF-GMS had a sustained-release property and fluoride release rate was increased in pH 4.5 artificial saliva. Experiments conducted in rabbits' oral cavity using NaF-GMS and NaF solution as control revealed NaF-GMS could maintain oral fluoride retention longer than NaF solution. Cariostatic abilities of NaF-GMS including demineralization prohibition in vitro, fluoride deposition in artificial dental plaque and the ability of targeting to cariogenic bacteria were investigated in artificial dental plaque. The results indicated NaF-GMS with lower fluoride concentrations could achieve equivalent cariostatic effect to the concentrated NaF solution, at the same time, could prolong fluoride retention in dental plaque. Microscopic observation showed that NaF-GMS carrying fusion protein of glucan-binding domain could adhere more bacteria than NaF-GMS and this might indicate the possibility of targeting to cariogenic bacteria when NaF-GMS were properly modified. © 2004 Taylor & Francis Ltd. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | DEMINERALIZATION |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | DENTAL CARIES |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | DENTAL PLAQUE |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | GELATIN MICROSPHERES |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | SODIUM FLUORIDE |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | SUSTAINED-RELEASE |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Wu H. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Zhang Z.X. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Zhao H.P. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Wu D.C. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Wu B.L. |
| 700 12 - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Cong R. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://drive.google.com/file/d/1I7JgtDWulHI0GQoPFEKaz3rURF3CMnX0/view?usp=drivesdk">https://drive.google.com/file/d/1I7JgtDWulHI0GQoPFEKaz3rURF3CMnX0/view?usp=drivesdk</a> |
| Public note | Para ver el documento ingresa a Google con tu cuenta @cicy.edu.mx |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Clasificación local |
| Koha item type | Documentos solicitados |
| Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Collection | Home library | Current library | Shelving location | Date acquired | Total checkouts | Full call number | Date last seen | Price effective from | Koha item type |
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| Clasificación local | Ref1 | CICY | CICY | Documento préstamo interbibliotecario | 25.06.2025 | B-21283 | 25.06.2025 | 25.06.2025 | Documentos solicitados |