Reconstitution and optimization of complex plant natural product biosynthetic pathways in microbial expression systems (Record no. 55356)

MARC details
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fixed length control field 01644nam a2200205Ia 4500
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control field MX-MdCICY
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250625164352.0
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Transcribing agency CICY
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Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-21288
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Title Reconstitution and optimization of complex plant natural product biosynthetic pathways in microbial expression systems
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Series statement Current Opinion in Biotechnology. 87, 103136, 2024, DOI: 10.1016/j.copbio.2024.103136
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Summary, etc. Plant natural products (PNPs) are a diverse group of chemical compounds synthesized by plants for various biological purposes and play a significant role in the fields of medicine, agriculture, and industry. In recent years, the development of synthetic biology promises the production of PNPs in microbial expression systems in a sustainable, low-cost, and large-scale manner. This review first introduces multiplex genome editing and PNP pathway assembly in microbial expression systems. Then recent technologies and examples geared toward improving PNP biosynthetic efficiency are discussed from three aspects: pathway optimization, chassis optimization, and modular coculture engineering. Finally, the review is concluded with future perspectives on the combination of machine learning and BioFoundry for the reconstitution and optimization of PNP microbial cell factories. © 2024 Elsevier Ltd
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Personal name Gao J.
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Personal name Gou Y.
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Personal name Huang L.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Lian J.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1g54uQ0eXA7jIrYEmAW6MNqOVRsFrIkhl/view?usp=drivesdk">https://drive.google.com/file/d/1g54uQ0eXA7jIrYEmAW6MNqOVRsFrIkhl/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta @cicy.edu.mx
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Source of classification or shelving scheme Clasificación local
Koha item type Documentos solicitados
Holdings
Lost status Source of classification or shelving scheme Damaged status Not for loan Collection Home library Current library Shelving location Date acquired Total checkouts Full call number Date last seen Price effective from Koha item type
  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-21288 25.06.2025 25.06.2025 Documentos solicitados